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Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease.
Martinelli F, Heinken A, Henning AK, Ulmer MA, Hensen T, González A, Arnold M, Asthana S, Budde K, Engelman CD, Estaki M, Grabe HJ, Heston MB, Johnson S, Kastenmüller G, Martino C, McDonald D, Rey FE, Kilimann I, Peters O, Wang X, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Glanz W, Buerger K, Janowitz D, Laske C, Munk MH, Spottke A, Roy N, Nauck M, Teipel S, Knight R, Kaddurah-Daouk RF, Bendlin BB, Hertel J, Thiele I. Martinelli F, et al. Among authors: arnold m. Sci Rep. 2024 Mar 13;14(1):6095. doi: 10.1038/s41598-024-55960-3. Sci Rep. 2024. PMID: 38480804 Free PMC article.
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease.
Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, Heinken A, Jia W, Mahmoudiandehkordi S, Louie G, Saykin AJ, Arnold M, Kastenmüller G, Griffiths WJ, Thiele I; Alzheimer’s Disease Metabolomics Consortium; Kaddurah-Daouk R, Price ND. Baloni P, et al. Among authors: arnold m. Cell Rep Med. 2020 Nov 17;1(8):100138. doi: 10.1016/j.xcrm.2020.100138. eCollection 2020 Nov 17. Cell Rep Med. 2020. PMID: 33294859 Free PMC article.
Peripheral serum metabolomic profiles inform central cognitive impairment.
Wang J, Wei R, Xie G, Arnold M, Kueider-Paisley A, Louie G, Mahmoudian Dehkordi S, Blach C, Baillie R, Han X, De Jager PL, Bennett DA, Kaddurah-Daouk R, Jia W. Wang J, et al. Among authors: arnold m. Sci Rep. 2020 Aug 20;10(1):14059. doi: 10.1038/s41598-020-70703-w. Sci Rep. 2020. PMID: 32820198 Free PMC article.
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Horgusluoglu E, Neff R, Song WM, Wang M, Wang Q, Arnold M, Krumsiek J, Galindo-Prieto B, Ming C, Nho K, Kastenmüller G, Han X, Baillie R, Zeng Q, Andrews S, Cheng H, Hao K, Goate A, Bennett DA, Saykin AJ, Kaddurah-Daouk R, Zhang B; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Metabolomics Consortium. Horgusluoglu E, et al. Among authors: arnold m. Alzheimers Dement. 2022 Jun;18(6):1260-1278. doi: 10.1002/alz.12468. Epub 2021 Nov 10. Alzheimers Dement. 2022. PMID: 34757660 Free PMC article.
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling MA, Motsinger-Reif A, Rotroff DM, Jack J, Hankemeier T, Bennett DA, De Jager PL, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, van Duijn CM, Saykin AJ, Kastenmüller G, Kaddurah-Daouk R; Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium. MahmoudianDehkordi S, et al. Among authors: arnold m. Alzheimers Dement. 2019 Jan;15(1):76-92. doi: 10.1016/j.jalz.2018.07.217. Epub 2018 Oct 15. Alzheimers Dement. 2019. PMID: 30337151 Free PMC article.
Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts.
St John-Williams L, Mahmoudiandehkordi S, Arnold M, Massaro T, Blach C, Kastenmüller G, Louie G, Kueider-Paisley A, Han X, Baillie R, Motsinger-Reif AA, Rotroff D, Nho K, Saykin AJ, Risacher SL, Koal T, Moseley MA, Tenenbaum JD, Thompson JW, Kaddurah-Daouk R; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium. St John-Williams L, et al. Among authors: arnold m. Sci Data. 2019 Oct 17;6(1):212. doi: 10.1038/s41597-019-0181-8. Sci Data. 2019. PMID: 31624257 Free PMC article.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: arnold m. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy.
Batra R, Krumsiek J, Wang X, Allen M, Blach C, Kastenmüller G, Arnold M, Ertekin-Taner N, Kaddurah-Daouk RF; Alzheimer’s Disease Metabolomics Consortium (ADMC). Batra R, et al. Among authors: arnold m. medRxiv [Preprint]. 2023 Jul 27:2023.07.25.23293055. doi: 10.1101/2023.07.25.23293055. medRxiv. 2023. PMID: 37546878 Free PMC article. Preprint.
2,870 results