Edelmann MR - Search Results

1

Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody Distribution.

Opolka-Hoffmann E, Edelmann MR, Otteneder MB, Hauri S, Jordan G, Schrag P, Lechmann M, Winter G, Staack RF. Opolka-Hoffmann E, et al. Among authors: edelmann mr. AAPS J. 2024 Mar 13;26(2):33. doi: 10.1208/s12248-024-00899-6. AAPS J. 2024. PMID: 38478197

2

Functional in vitro assessment of modified antibodies: Impact of label on protein properties.

Edelmann MR, Hauri S. Edelmann MR, et al. PLoS One. 2021 Sep 16;16(9):e0257342. doi: 10.1371/journal.pone.0257342. eCollection 2021. PLoS One. 2021. PMID: 34529712 Free PMC article.

3

Radiolabeled IgG antibodies: Impact of various labels on neonatal Fc receptor binding.

Edelmann MR, Kettenberger H, Knaupp A, Schlothauer T, Otteneder MB. Edelmann MR, et al. J Labelled Comp Radiopharm. 2019 Sep;62(11):751-757. doi: 10.1002/jlcr.3793. Epub 2019 Aug 13. J Labelled Comp Radiopharm. 2019. PMID: 31369163

4

Are Biotransformation Studies of Therapeutic Proteins Needed? Scientific Considerations and Technical Challenges.

Schadt S, Hauri S, Lopes F, Edelmann MR, Staack RF, Villaseñor R, Kettenberger H, Roth AB, Schuler F, Richter WF, Funk C. Schadt S, et al. Among authors: edelmann mr. Drug Metab Dispos. 2019 Dec;47(12):1443-1456. doi: 10.1124/dmd.119.088997. Drug Metab Dispos. 2019. PMID: 31748266

5

Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms.

Jaramillo CAC, Belli S, Cascais AC, Dudal S, Edelmann MR, Haak M, Brun ME, Otteneder MB, Ullah M, Funk C, Schuler F, Simon S. Jaramillo CAC, et al. Among authors: edelmann mr. MAbs. 2017 Jul;9(5):781-791. doi: 10.1080/19420862.2017.1320008. Epub 2017 Apr 25. MAbs. 2017. PMID: 28440708 Free PMC article.

6

Evaluation of Tetrazine Tracers for Pretargeted Imaging within the Central Nervous System.

Edelmann MR, Bredack C, Belli S, Mohr P, Imhoff MP, Reggiani F, Kusznir EA, Rufer AC, Holt DP, Valentine H, Wong DF, Dannals RF, Honer M, Gobbi LC. Edelmann MR, et al. Bioconjug Chem. 2023 Oct 18;34(10):1882-1893. doi: 10.1021/acs.bioconjchem.3c00385. Epub 2023 Sep 14. Bioconjug Chem. 2023. PMID: 37710950

7

Radiolabelling small and biomolecules for tracking and monitoring.

Edelmann MR. Edelmann MR. RSC Adv. 2022 Nov 11;12(50):32383-32400. doi: 10.1039/d2ra06236d. eCollection 2022 Nov 9. RSC Adv. 2022. PMID: 36425706 Free PMC article. Review.

8

Antibody-Based In Vivo Imaging of Central Nervous System Targets-Evaluation of a Pretargeting Approach Utilizing a TCO-Conjugated Brain Shuttle Antibody and Radiolabeled Tetrazines.

Bredack C, Edelmann MR, Borroni E, Gobbi LC, Honer M. Bredack C, et al. Among authors: edelmann mr. Pharmaceuticals (Basel). 2022 Nov 22;15(12):1445. doi: 10.3390/ph15121445. Pharmaceuticals (Basel). 2022. PMID: 36558900 Free PMC article.

9

Tritium O-Methylation of N-Alkoxy Maleimide Derivatives as Labeling Reagents for Biomolecules.

Edelmann MR, Muser T. Edelmann MR, et al. Bioconjug Chem. 2021 May 19;32(5):1027-1033. doi: 10.1021/acs.bioconjchem.1c00202. Epub 2021 Apr 28. Bioconjug Chem. 2021. PMID: 33909418

10

Tritium Labeling of Neuromedin S by Conjugation with [³H]N-Succinimidyl Propionate.

Edelmann MR, Erny J, Guba W, Hierl M. Edelmann MR, et al. ACS Omega. 2023 Jan 4;8(2):2367-2376. doi: 10.1021/acsomega.2c06758. eCollection 2023 Jan 17. ACS Omega. 2023. PMID: 36687043 Free PMC article.

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