Waldmann H - Search Results

1

Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.

Dötsch L, Davies C, Hennes E, Schönfeld J, Kumar A, Guita CDCL, Ehrler JHM, Hiesinger K, Thavam S, Janning P, Sievers S, Knapp S, Proschak E, Ziegler S, Waldmann H. Dötsch L, et al. Among authors: waldmann h. J Med Chem. 2024 Mar 28;67(6):4691-4706. doi: 10.1021/acs.jmedchem.3c02245. Epub 2024 Mar 12. J Med Chem. 2024. PMID: 38470246 Free PMC article.

2

Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases.

Seibert SF, Eguereva E, Krick A, Kehraus S, Voloshina E, Raabe G, Fleischhauer J, Leistner E, Wiese M, Prinz H, Alexandrov K, Janning P, Waldmann H, König GM. Seibert SF, et al. Among authors: waldmann h. Org Biomol Chem. 2006 Jun 7;4(11):2233-40. doi: 10.1039/b601386d. Epub 2006 May 3. Org Biomol Chem. 2006. PMID: 16729132

3

Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.

Müller D, Krick A, Kehraus S, Mehner C, Hart M, Küpper FC, Saxena K, Prinz H, Schwalbe H, Janning P, Waldmann H, König GM. Müller D, et al. Among authors: waldmann h. J Med Chem. 2006 Aug 10;49(16):4871-8. doi: 10.1021/jm060327w. J Med Chem. 2006. PMID: 16884299

4

The Ras pathway modulator melophlin A targets dynamins.

Knoth T, Warburg K, Katzka C, Rai A, Wolf A, Brockmeyer A, Janning P, Reubold TF, Eschenburg S, Manstein DJ, Hübel K, Kaiser M, Waldmann H. Knoth T, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2009;48(39):7240-5. doi: 10.1002/anie.200902023. Angew Chem Int Ed Engl. 2009. PMID: 19722243 No abstract available.

5

Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors.

Tan KT, Guiu-Rozas E, Bon RS, Guo Z, Delon C, Wetzel S, Arndt S, Alexandrov K, Waldmann H, Goody RS, Wu YW, Blankenfeldt W. Tan KT, et al. Among authors: waldmann h. J Med Chem. 2009 Dec 24;52(24):8025-37. doi: 10.1021/jm901117d. J Med Chem. 2009. PMID: 19894725

6

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products.

Antonchick AP, Gerding-Reimers C, Catarinella M, Schürmann M, Preut H, Ziegler S, Rauh D, Waldmann H. Antonchick AP, et al. Among authors: waldmann h. Nat Chem. 2010 Sep;2(9):735-40. doi: 10.1038/nchem.730. Epub 2010 Jul 11. Nat Chem. 2010. PMID: 20729892

7

Using small molecules to target protein phosphatases.

Vintonyak VV, Waldmann H, Rauh D. Vintonyak VV, et al. Among authors: waldmann h. Bioorg Med Chem. 2011 Apr 1;19(7):2145-55. doi: 10.1016/j.bmc.2011.02.047. Epub 2011 Mar 2. Bioorg Med Chem. 2011. PMID: 21420867

8

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.

Radtke L, Willot M, Sun H, Ziegler S, Sauerland S, Strohmann C, Fröhlich R, Habenberger P, Waldmann H, Christmann M. Radtke L, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3998-4002. doi: 10.1002/anie.201007790. Epub 2011 Mar 29. Angew Chem Int Ed Engl. 2011. PMID: 21472928 No abstract available.

9

Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

Dückert H, Pries V, Khedkar V, Menninger S, Bruss H, Bird AW, Maliga Z, Brockmeyer A, Janning P, Hyman A, Grimme S, Schürmann M, Preut H, Hübel K, Ziegler S, Kumar K, Waldmann H. Dückert H, et al. Among authors: waldmann h. Nat Chem Biol. 2011 Dec 25;8(2):179-84. doi: 10.1038/nchembio.758. Nat Chem Biol. 2011. PMID: 22198731

10

Charting, navigating, and populating natural product chemical space for drug discovery.

Lachance H, Wetzel S, Kumar K, Waldmann H. Lachance H, et al. Among authors: waldmann h. J Med Chem. 2012 Jul 12;55(13):5989-6001. doi: 10.1021/jm300288g. Epub 2012 May 11. J Med Chem. 2012. PMID: 22537178 Review.

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