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Bi-specific autoantigen-T cell engagers as targeted immunotherapy for autoreactive B cell depletion in autoimmune diseases.
Perico L, Casiraghi F, Sônego F, Todeschini M, Corna D, Cerullo D, Pezzotta A, Isnard-Petit P, Faravelli S, Forneris F, Thiam K, Benigni A, Remuzzi G. Perico L, et al. Among authors: todeschini m. Front Immunol. 2024 Feb 26;15:1335998. doi: 10.3389/fimmu.2024.1335998. eCollection 2024. Front Immunol. 2024. PMID: 38469301 Free PMC article.
In kidney transplant patients, alemtuzumab but not basiliximab/low-dose rabbit anti-thymocyte globulin induces B cell depletion and regeneration, which associates with a high incidence of de novo donor-specific anti-HLA antibody development.
Todeschini M, Cortinovis M, Perico N, Poli F, Innocente A, Cavinato RA, Gotti E, Ruggenenti P, Gaspari F, Noris M, Remuzzi G, Casiraghi F. Todeschini M, et al. J Immunol. 2013 Sep 1;191(5):2818-28. doi: 10.4049/jimmunol.1203261. Epub 2013 Aug 2. J Immunol. 2013. PMID: 23913968 Clinical Trial.
Molecular Studies and an ex vivo Complement Assay on Endothelium Highlight the Genetic Complexity of Atypical Hemolytic Uremic Syndrome: The Case of a Pedigree With a Null CD46 Variant.
Piras R, Iatropoulos P, Bresin E, Todeschini M, Gastoldi S, Valoti E, Alberti M, Mele C, Galbusera M, Cuccarolo P, Benigni A, Remuzzi G, Noris M. Piras R, et al. Among authors: todeschini m. Front Med (Lausanne). 2020 Nov 3;7:579418. doi: 10.3389/fmed.2020.579418. eCollection 2020. Front Med (Lausanne). 2020. PMID: 33224962 Free PMC article.
89 results