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Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease.
Gabriel GC, Yagi H, Tan T, Bais AS, Glennon BJ, Stapleton MC, Huang L, Reynolds WT, Shaffer MG, Ganapathiraju M, Simon D, Panigrahy A, Wu YL, Lo CW. Gabriel GC, et al. Among authors: ganapathiraju m. bioRxiv [Preprint]. 2024 Feb 26:2023.11.05.565716. doi: 10.1101/2023.11.05.565716. bioRxiv. 2024. PMID: 38464057 Free PMC article. Preprint.
Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW. Li Y, et al. Among authors: ganapathiraju mk. Nature. 2015 May 28;521(7553):520-4. doi: 10.1038/nature14269. Epub 2015 Mar 25. Nature. 2015. PMID: 25807483 Free PMC article.
The complex genetics of hypoplastic left heart syndrome.
Liu X, Yagi H, Saeed S, Bais AS, Gabriel GC, Chen Z, Peterson KA, Li Y, Schwartz MC, Reynolds WT, Saydmohammed M, Gibbs B, Wu Y, Devine W, Chatterjee B, Klena NT, Kostka D, de Mesy Bentley KL, Ganapathiraju MK, Dexheimer P, Leatherbury L, Khalifa O, Bhagat A, Zahid M, Pu W, Watkins S, Grossfeld P, Murray SA, Porter GA Jr, Tsang M, Martin LJ, Benson DW, Aronow BJ, Lo CW. Liu X, et al. Among authors: ganapathiraju mk. Nat Genet. 2017 Jul;49(7):1152-1159. doi: 10.1038/ng.3870. Epub 2017 May 22. Nat Genet. 2017. PMID: 28530678 Free PMC article.
Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease.
Xu X, Jin K, Bais AS, Zhu W, Yagi H, Feinstein TN, Nguyen PK, Criscione JD, Liu X, Beutner G, Karunakaran KB, Rao KS, He H, Adams P, Kuo CK, Kostka D, Pryhuber GS, Shiva S, Ganapathiraju MK, Porter GA Jr, Lin JI, Aronow B, Lo CW. Xu X, et al. Among authors: ganapathiraju mk. Cell Stem Cell. 2022 May 5;29(5):840-855.e7. doi: 10.1016/j.stem.2022.03.003. Epub 2022 Apr 7. Cell Stem Cell. 2022. PMID: 35395180 Free PMC article.
The Role of Cilia and the Complex Genetics of Congenital Heart Disease.
Gabriel GC, Ganapathiraju M, Lo CW. Gabriel GC, et al. Among authors: ganapathiraju m. Annu Rev Genomics Hum Genet. 2024 May 9. doi: 10.1146/annurev-genom-121222-105345. Online ahead of print. Annu Rev Genomics Hum Genet. 2024. PMID: 38724024 Review.
Flow blockage disrupts cilia-driven fluid transport in the epileptic brain.
Faubel RJ, Santos Canellas VS, Gaesser J, Beluk NH, Feinstein TN, Wang Y, Yankova M, Karunakaran KB, King SM, Ganapathiraju MK, Lo CW. Faubel RJ, et al. Among authors: ganapathiraju mk. Acta Neuropathol. 2022 Oct;144(4):691-706. doi: 10.1007/s00401-022-02463-y. Epub 2022 Aug 18. Acta Neuropathol. 2022. PMID: 35980457
Author Correction: Parkinson's disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes.
Karunakaran KB, Jain S, Brahmachari SK, Balakrishnan N, Ganapathiraju MK. Karunakaran KB, et al. Among authors: ganapathiraju mk. Schizophrenia (Heidelb). 2024 Mar 13;10(1):33. doi: 10.1038/s41537-024-00455-3. Schizophrenia (Heidelb). 2024. PMID: 38480791 Free PMC article. No abstract available.
46 results