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FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration.
Kodavati M, Wang H, Guo W, Mitra J, Hegde PM, Provasek V, Maloji Rao VH, Vedula I, Zhang A, Mitra S, Tomkinson AE, Hamilton DJ, Bosch LVD, Hegde ML. Kodavati M, et al. Among authors: tomkinson ae. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-3152718. doi: 10.21203/rs.3.rs-3152718/v1. Res Sq. 2023. PMID: 37502965 Free PMC article. Updated. Preprint.
The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD.
Hegde PM, Dutta A, Sengupta S, Mitra J, Adhikari S, Tomkinson AE, Li GM, Boldogh I, Hazra TK, Mitra S, Hegde ML. Hegde PM, et al. Among authors: tomkinson ae. J Biol Chem. 2015 Aug 21;290(34):20919-20933. doi: 10.1074/jbc.M115.642918. Epub 2015 Jul 1. J Biol Chem. 2015. PMID: 26134572 Free PMC article.
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2.
Dey S, Maiti AK, Hegde ML, Hegde PM, Boldogh I, Sarkar PS, Abdel-Rahman SZ, Sarker AH, Hang B, Xie J, Tomkinson AE, Zhou M, Shen B, Wang G, Wu C, Yu D, Lin D, Cardenas V, Hazra TK. Dey S, et al. Among authors: tomkinson ae. DNA Repair (Amst). 2012 Jun 1;11(6):570-8. doi: 10.1016/j.dnarep.2012.03.005. Epub 2012 Apr 10. DNA Repair (Amst). 2012. PMID: 22497777 Free PMC article.
The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites.
Della-Maria J, Hegde ML, McNeill DR, Matsumoto Y, Tsai MS, Ellenberger T, Wilson DM 3rd, Mitra S, Tomkinson AE. Della-Maria J, et al. Among authors: tomkinson ae. J Biol Chem. 2012 Nov 9;287(46):39233-44. doi: 10.1074/jbc.M112.369975. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992732 Free PMC article.
Altered DNA ligase activity in human disease.
Tomkinson AE, Naila T, Khattri Bhandari S. Tomkinson AE, et al. Mutagenesis. 2020 Feb 13;35(1):51-60. doi: 10.1093/mutage/gez026. Mutagenesis. 2020. PMID: 31630206 Free PMC article. Review.
147 results