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TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
Creus-Muncunill J, Haure-Mirande JV, Mattei D, Bons J, Ramirez AV, Hamilton BW, Corwin C, Chowdhury S, Schilling B, Ellerby LM, Ehrlich ME. Creus-Muncunill J, et al. Among authors: ellerby lm. J Neuroinflammation. 2024 Mar 8;21(1):66. doi: 10.1186/s12974-024-03052-4. J Neuroinflammation. 2024. PMID: 38459557 Free PMC article.
Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.
Tshilenge KT, Aguirre CG, Bons J, Gerencser AA, Basisty N, Song S, Rose J, Lopez-Ramirez A, Naphade S, Loureiro A, Battistoni E, Milani M, Wehrfritz C, Holtz A, Hetz C, Mooney SD, Schilling B, Ellerby LM. Tshilenge KT, et al. Among authors: ellerby lm. Mol Cell Proteomics. 2023 May;22(5):100534. doi: 10.1016/j.mcpro.2023.100534. Epub 2023 Mar 22. Mol Cell Proteomics. 2023. PMID: 36958627 Free PMC article.
Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction.
Bar S, Wilson KA, Hilsabeck TAU, Alderfer S, Dammer EB, Burton JB, Shah S, Holtz A, Carrera EM, Beck JN, Chen JH, Kauwe G, Tracy TE, Seyfried NT, Schilling B, Ellerby LM, Kapahi P. Bar S, et al. Among authors: ellerby lm. Res Sq [Preprint]. 2023 Nov 8:rs.3.rs-3526342. doi: 10.21203/rs.3.rs-3526342/v1. Res Sq. 2023. PMID: 37986935 Free PMC article. Preprint.
Judith Campisi (1948-2024).
Melov S, Schilling B, Ellerby LM, Kapahi P. Melov S, et al. Among authors: ellerby lm. Nat Cell Biol. 2024 Apr;26(4):504-505. doi: 10.1038/s41556-024-01396-w. Nat Cell Biol. 2024. PMID: 38589533 No abstract available.
Single-cell transcriptomics reveals colonic immune perturbations during amyloid-β driven Alzheimer's disease in mice.
Makhijani P, Emani R, Aguirre CG, Mu WC, Rane A, Ng JHY, Valentino TR, Manwaring-Mueller M, Tan CR, Du H, Wu F, Khan S, Wilson KA, Winer S, Wang C, Mortha A, Furman D, Ellerby LM, Rojas OL, Andersen JK, Winer DA. Makhijani P, et al. Among authors: ellerby lm. bioRxiv [Preprint]. 2024 Jan 30:2024.01.27.573841. doi: 10.1101/2024.01.27.573841. bioRxiv. 2024. PMID: 38352325 Free PMC article. Preprint.
OXR1 maintains the retromer to delay brain aging under dietary restriction.
Wilson KA, Bar S, Dammer EB, Carrera EM, Hodge BA, Hilsabeck TAU, Bons J, Brownridge GW 3rd, Beck JN, Rose J, Granath-Panelo M, Nelson CS, Qi G, Gerencser AA, Lan J, Afenjar A, Chawla G, Brem RB, Campeau PM, Bellen HJ, Schilling B, Seyfried NT, Ellerby LM, Kapahi P. Wilson KA, et al. Among authors: ellerby lm. Nat Commun. 2024 Jan 11;15(1):467. doi: 10.1038/s41467-023-44343-3. Nat Commun. 2024. PMID: 38212606 Free PMC article.
104 results