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The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
He X, Zhang X, Wu B, Deng J, Zhang Y, Zhu A, Yuan Y, Lin Y, Chen A, Feng J, Wang X, Wu S, Liu Y, Liu J, Wang Y, Li R, Liang C, Yuan Q, Liang Y, Fang Q, Xi Z, Li W, Liang L, Zhang Z, Tang H, Peng Y, Ke C, Ma X, Cai W, Pan T, Liu B, Deng K, Chen J, Zhao J, Wei X, Chen R, Zhang Y, Zhang H. He X, et al. Among authors: deng k, deng j. Nat Immunol. 2024 Apr;25(4):622-632. doi: 10.1038/s41590-024-01776-2. Epub 2024 Mar 7. Nat Immunol. 2024. PMID: 38454157
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
Ma X, Yang T, Luo Y, Wu L, Jiang Y, Song Z, Pan T, Liu B, Liu G, Liu J, Yu F, He Z, Zhang W, Yang J, Liang L, Guan Y, Zhang X, Li L, Cai W, Tang X, Gao S, Deng K, Zhang H. Ma X, et al. Among authors: deng k. Elife. 2019 Jan 17;8:e42426. doi: 10.7554/eLife.42426. Elife. 2019. PMID: 30652970 Free PMC article.
Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef-AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells.
Liu B, Zhang X, Zhang W, Wu L, Jing S, Liu W, Xia B, Zou F, Lu L, Ma X, He D, Hu Q, Zhang Y, Deng K, Cai W, Tang X, Peng T, Zhang H, Li L. Liu B, et al. Among authors: deng k. Front Immunol. 2019 Sep 10;10:2151. doi: 10.3389/fimmu.2019.02151. eCollection 2019. Front Immunol. 2019. PMID: 31572371 Free PMC article.
Recovered COVID-19 patients with recurrent viral RNA exhibit lower levels of anti-RBD antibodies.
Liu B, Shi Y, Zhang W, Li R, He Z, Yang X, Pan Y, Deng X, Tan M, Zhao L, Zou F, Zhang Y, Pan T, Zhang J, Zhang X, Xiao F, Li F, Deng K, Zhang H. Liu B, et al. Among authors: deng k, deng x. Cell Mol Immunol. 2020 Oct;17(10):1098-1100. doi: 10.1038/s41423-020-00528-0. Epub 2020 Sep 16. Cell Mol Immunol. 2020. PMID: 32939033 Free PMC article. No abstract available.
A bivalent nanoparticle vaccine exhibits potent cross-protection against the variants of SARS-CoV-2.
Yuan Y, Zhang X, Chen R, Li Y, Wu B, Li R, Zou F, Ma X, Wang X, Chen Q, Deng J, Zhang Y, Chen T, Lin Y, Yan S, Zhang X, Li C, Bu X, Peng Y, Ke C, Deng K, Pan T, He X, Zhang Y, Zhang H. Yuan Y, et al. Among authors: deng k, deng j. Cell Rep. 2022 Jan 18;38(3):110256. doi: 10.1016/j.celrep.2021.110256. Epub 2021 Dec 23. Cell Rep. 2022. PMID: 34990583 Free PMC article.
Development of Receptor Binding Domain (RBD)-Conjugated Nanoparticle Vaccines with Broad Neutralization against SARS-CoV-2 Delta and Other Variants.
Chen R, Zhang X, Yuan Y, Deng X, Wu B, Xi Z, Wang G, Lin Y, Li R, Wang X, Zou F, Liang L, Yan H, Liang C, Li Y, Wu S, Deng J, Zhou M, Zhang X, Li C, Bu X, Peng Y, Ke C, Deng K, He X, Zhang Y, Zhang Z, Pan T, Zhang H. Chen R, et al. Among authors: deng k, deng j, deng x. Adv Sci (Weinh). 2022 Apr;9(11):e2105378. doi: 10.1002/advs.202105378. Epub 2022 Feb 10. Adv Sci (Weinh). 2022. PMID: 35142444 Free PMC article.
2,117 results