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Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease.
Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW. Wilmanns JC, et al. Among authors: costa mw. Mol Metab. 2019 Feb;20:102-114. doi: 10.1016/j.molmet.2018.11.002. Epub 2018 Nov 15. Mol Metab. 2019. PMID: 30482476 Free PMC article.
Adult mouse fibroblasts retain organ-specific transcriptomic identity.
Forte E, Ramialison M, Nim HT, Mara M, Li JY, Cohn R, Daigle SL, Boyd S, Stanley EG, Elefanty AG, Hinson JT, Costa MW, Rosenthal NA, Furtado MB. Forte E, et al. Among authors: costa mw. Elife. 2022 Mar 16;11:e71008. doi: 10.7554/eLife.71008. Elife. 2022. PMID: 35293863 Free PMC article.
CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts.
Nim HT, Furtado MB, Costa MW, Kitano H, Rosenthal NA, Boyd SE. Nim HT, et al. Among authors: costa mw. PLoS One. 2015 Dec 16;10(12):e0143274. doi: 10.1371/journal.pone.0143274. eCollection 2015. PLoS One. 2015. PMID: 26673252 Free PMC article.
Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy.
Choquet C, Nguyen THM, Sicard P, Buttigieg E, Tran TT, Kober F, Varlet I, Sturny R, Costa MW, Harvey RP, Nguyen C, Rihet P, Richard S, Bernard M, Kelly RG, Lalevée N, Miquerol L. Choquet C, et al. Among authors: costa mw. PLoS Genet. 2018 Jul 6;14(7):e1007502. doi: 10.1371/journal.pgen.1007502. eCollection 2018 Jul. PLoS Genet. 2018. PMID: 29979676 Free PMC article.
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.
Anderson DJ, Kaplan DI, Bell KM, Koutsis K, Haynes JM, Mills RJ, Phelan DG, Qian EL, Leitoguinho AR, Arasaratnam D, Labonne T, Ng ES, Davis RP, Casini S, Passier R, Hudson JE, Porrello ER, Costa MW, Rafii A, Curl CL, Delbridge LM, Harvey RP, Oshlack A, Cheung MM, Mummery CL, Petrou S, Elefanty AG, Stanley EG, Elliott DA. Anderson DJ, et al. Among authors: costa mw. Nat Commun. 2018 Apr 10;9(1):1373. doi: 10.1038/s41467-018-03714-x. Nat Commun. 2018. PMID: 29636455 Free PMC article.
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.
Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: costa mw. JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271. JCI Insight. 2017. PMID: 28352650 Free PMC article.
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart.
Mohenska M, Tan NM, Tokolyi A, Furtado MB, Costa MW, Perry AJ, Hatwell-Humble J, van Duijvenboden K, Nim HT, Ji YMM, Charitakis N, Bienroth D, Bolk F, Vivien C, Knaupp AS, Powell DR, Elliott DA, Porrello ER, Nilsson SK, Del Monte-Nieto G, Rosenthal NA, Rossello FJ, Polo JM, Ramialison M. Mohenska M, et al. Among authors: costa mw. J Mol Cell Cardiol. 2022 Feb;163:20-32. doi: 10.1016/j.yjmcc.2021.09.011. Epub 2021 Oct 5. J Mol Cell Cardiol. 2022. PMID: 34624332
39 results