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BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival.
Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, Im DS, Callaghan S, Dewar-Darch D, Figeys D, Slack RS, Park DS. Qu D, et al. Among authors: hewitt sj. J Biol Chem. 2015 Dec 18;290(51):30441-52. doi: 10.1074/jbc.M115.677815. Epub 2015 Nov 4. J Biol Chem. 2015. PMID: 26538564 Free PMC article.
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, Kim RH, Chen CX, Fon EA, Slack RS, Harper ME, McBride HM, Mak TW, Park DS. Irrcher I, et al. Among authors: hewitt sj. Hum Mol Genet. 2010 Oct 1;19(19):3734-46. doi: 10.1093/hmg/ddq288. Epub 2010 Jul 16. Hum Mol Genet. 2010. PMID: 20639397
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.
Aleyasin H, Rousseaux MW, Marcogliese PC, Hewitt SJ, Irrcher I, Joselin AP, Parsanejad M, Kim RH, Rizzu P, Callaghan SM, Slack RS, Mak TW, Park DS. Aleyasin H, et al. Among authors: hewitt sj. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3186-91. doi: 10.1073/pnas.0914876107. Epub 2010 Jan 26. Proc Natl Acad Sci U S A. 2010. PMID: 20133695 Free PMC article.