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Tailoring lipid nanoparticles for T-cell targeting in allergic asthma: Insights into efficacy and specificity.
Eur J Pharm Biopharm. 2024 May;198:114242. doi: 10.1016/j.ejpb.2024.114242. Epub 2024 Mar 3.
Eur J Pharm Biopharm. 2024.
PMID: 38442794
Free article.
Evaluation of the effects of storage conditions on spray-dried siRNA-LNPs before and after subsequent drying.
Zimmermann CM, Deßloch L, Jürgens DC, Luciani P, Merkel OM.
Zimmermann CM, et al. Among authors: jurgens dc.
Eur J Pharm Biopharm. 2023 Dec;193:218-226. doi: 10.1016/j.ejpb.2023.11.007. Epub 2023 Nov 11.
Eur J Pharm Biopharm. 2023.
PMID: 37956785
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Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma.
Kandil R, Baldassi D, Böhlen S, Müller JT, Jürgens DC, Bargmann T, Dehmel S, Xie Y, Mehta A, Sewald K, Merkel OM.
Kandil R, et al. Among authors: jurgens dc.
J Control Release. 2023 Feb;354:305-315. doi: 10.1016/j.jconrel.2023.01.014. Epub 2023 Jan 13.
J Control Release. 2023.
PMID: 36634709
Free PMC article.
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Protein corona investigations of polyplexes with varying hydrophobicity - From method development to in vitro studies.
Hartl N, Jürgens DC, Carneiro S, König AC, Xiao X, Liu R, Hauck SM, Merkel OM.
Hartl N, et al. Among authors: jurgens dc.
Int J Pharm. 2023 Aug 25;643:123257. doi: 10.1016/j.ijpharm.2023.123257. Epub 2023 Jul 22.
Int J Pharm. 2023.
PMID: 37482228
Free article.
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Efficient and Targeted siRNA Delivery to M2 Macrophages by Smart Polymer Blends for M1 Macrophage Repolarization as a Promising Strategy for Future Cancer Treatment.
Jürgens DC, Winkeljann B, Kolog Gulko M, Jin Y, Möller J, Winkeljann J, Sheshachala S, Anger A, Hörner A, Adams NBP, Urbanetz N, Merkel OM.
Jürgens DC, et al.
ACS Biomater Sci Eng. 2024 Jan 8;10(1):166-177. doi: 10.1021/acsbiomaterials.3c01595. Epub 2023 Nov 18.
ACS Biomater Sci Eng. 2024.
PMID: 37978912
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Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis.
Adams F, Zimmermann CM, Baldassi D, Pehl TM, Weingarten P, Kachel I, Kränzlein M, Jürgens DC, Braubach P, Alexopoulos I, Wygrecka M, Merkel OM.
Adams F, et al. Among authors: jurgens dc.
Small. 2024 May;20(22):e2308775. doi: 10.1002/smll.202308775. Epub 2023 Dec 21.
Small. 2024.
PMID: 38126895
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