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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
Gu Y, Shunmuganathan B, Qian X, Gupta R, Tan RSW, Kozma M, Purushotorman K, Murali TM, Tan NYJ, Preiser PR, Lescar J, Nasir H, Somani J, Tambyah PA; SCOPE Cohort Study Group; Smith KGC, Renia L, Ng LFP, Lye DC, Young BE, MacAry PA. Gu Y, et al. Sci Rep. 2023 Dec 9;13(1):21810. doi: 10.1038/s41598-023-49231-w. Sci Rep. 2023. PMID: 38071323 Free PMC article.
Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose.
Renia L, Goh YS, Rouers A, Le Bert N, Chia WN, Chavatte JM, Fong SW, Chang ZW, Zhuo NZ, Tay MZ, Chan YH, Tan CW, Yeo NK, Amrun SN, Huang Y, Wong JXE, Hor PX, Loh CY, Wang B, Ngoh EZX, Salleh SNM, Carissimo G, Dowla S, Lim AJ, Zhang J, Lim JME, Wang CI, Ding Y, Pada S, Sun LJ, Somani J, Lee ES, Ong DLS; SCOPE Cohort Study Group; Leo YS, MacAry PA, Lin RTP, Wang LF, Ren EC, Lye DC, Bertoletti A, Young BE, Ng LFP. Renia L, et al. Nat Commun. 2022 Aug 8;13(1):4615. doi: 10.1038/s41467-022-32312-1. Nat Commun. 2022. PMID: 35941158 Free PMC article.
Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults.
Ho VWT, Boon LH, Cui J, Juequn Z, Shunmuganathan B, Gupta R, Tan NYJ, Qian X, Purushotorman K; SCOPE Cohort Study Group; Fong SW, Renia L, Ng LFP, Angeli V, Chen J, Kennedy BK, Ong CWM, Macary PA. Ho VWT, et al. Aging Cell. 2024 Apr;23(4):e14099. doi: 10.1111/acel.14099. Epub 2024 Feb 5. Aging Cell. 2024. PMID: 38317404 Free PMC article.
Pre-test Prediction of Non-ischemic Cardiomyopathies using Time-Series EHR Data.
Ishwaran K, Abadie BQ, Chen PH, Bolen M, Karamlou T, Grimm R, Tang WHW, Nguyen C, Kwon D, Chen D. Ishwaran K, et al. Among authors: tang whw. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:239-248. eCollection 2024. AMIA Jt Summits Transl Sci Proc. 2024. PMID: 38827049 Free PMC article.
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