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Protein kinase D activity is a risk biomarker in prostate cancer that drives cell invasion by a Snail/ERK dependent mechanism.
Cilleros-Rodríguez D, Toledo-Lobo MV, Martínez-Martínez D, Baquero P, Angulo JC, Chiloeches A, Iglesias T, Lasa M. Cilleros-Rodríguez D, et al. Among authors: baquero p. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166851. doi: 10.1016/j.bbadis.2023.166851. Epub 2023 Aug 21. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37611675 Free article.
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Dawson A, Zarou MM, Prasad B, Bittencourt-Silvestre J, Zerbst D, Himonas E, Hsieh YC, van Loon I, Blanco GR, Ianniciello A, Kerekes Z, Krishnan V, Agarwal P, Almasoudi H, McCluskey L, Hopcroft LEM, Scott MT, Baquero P, Dunn K, Vetrie D, Copland M, Bhatia R, Coffelt SB, Tiong OS, Wheadon H, Zanivan S, Kirschner K, Helgason GV. Dawson A, et al. Among authors: baquero p. Nat Commun. 2024 Feb 5;15(1):1090. doi: 10.1038/s41467-024-45471-0. Nat Commun. 2024. PMID: 38316788 Free PMC article.
Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer.
Martínez-Martínez D, Toledo Lobo MV, Baquero P, Ropero S, Angulo JC, Chiloeches A, Lasa M. Martínez-Martínez D, et al. Among authors: baquero p. Cancers (Basel). 2021 Mar 8;13(5):1158. doi: 10.3390/cancers13051158. Cancers (Basel). 2021. PMID: 33800291 Free PMC article.
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors.
Baquero P, Dawson A, Mukhopadhyay A, Kuntz EM, Mitchell R, Olivares O, Ianniciello A, Scott MT, Dunn K, Nicastri MC, Winkler JD, Michie AM, Ryan KM, Halsey C, Gottlieb E, Keaney EP, Murphy LO, Amaravadi RK, Holyoake TL, Helgason GV. Baquero P, et al. Leukemia. 2019 Apr;33(4):981-994. doi: 10.1038/s41375-018-0252-4. Epub 2018 Sep 5. Leukemia. 2019. PMID: 30185934 Free PMC article.
Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition.
Mitchell R, Hopcroft LEM, Baquero P, Allan EK, Hewit K, James D, Hamilton G, Mukhopadhyay A, O'Prey J, Hair A, Melo JV, Chan E, Ryan KM, Maguer-Satta V, Druker BJ, Clark RE, Mitra S, Herzyk P, Nicolini FE, Salomoni P, Shanks E, Calabretta B, Holyoake TL, Helgason GV. Mitchell R, et al. Among authors: baquero p. J Natl Cancer Inst. 2018 May 1;110(5):467-478. doi: 10.1093/jnci/djx236. J Natl Cancer Inst. 2018. PMID: 29165716 Free PMC article.
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