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Efficacy and safety of azacitidine in pediatric patients with newly diagnosed advanced myelodysplastic syndromes before hematopoietic stem cell transplantation in the AZA-JMML-001 trial.
Locatelli F, Strålin KB, Schmid I, Sevilla J, Smith OP, van den Heuvel-Eibrink MM, Zecca M, Zwaan CM, Gaudy A, Patturajan M, Poon J, Simcock M, Niemeyer CM. Locatelli F, et al. Among authors: smith op. Pediatr Blood Cancer. 2024 May;71(5):e30931. doi: 10.1002/pbc.30931. Epub 2024 Mar 3. Pediatr Blood Cancer. 2024. PMID: 38433307
Adapted risk stratification and intensive chemotherapy abrogate the poor prognosis of pediatric B acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (iAMP21): a National cohort analysis.
Trinquand A, Betts DR, Harte S, Sills A, Rooney S, Barrett N, Storey L, Malone A, O'Marcaigh A, Smith OP. Trinquand A, et al. Among authors: smith op. Leuk Lymphoma. 2024 Feb;65(2):279-282. doi: 10.1080/10428194.2023.2276061. Epub 2024 Jan 24. Leuk Lymphoma. 2024. PMID: 37909291 No abstract available.
Second allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft.
Vinci L, Flotho C, Noellke P, Lebrecht D, Masetti R, de Haas V, De Moerloose B, Dworzak M, Hasle H, Güngör T, Starý J, Turkiewicz D, Ussowicz M, de Heredia CD, Buechner J, Jahnukainen K, Kallay K, Bodova I, Smith OP, Zecca M, Bresters D, Lang P, Masmas TN, Meisel R, Pichler H, Erlacher M, Göhring G, Locatelli F, Strahm B, Niemeyer CM, Yoshimi A. Vinci L, et al. Among authors: smith op. Bone Marrow Transplant. 2023 May;58(5):607-609. doi: 10.1038/s41409-023-01942-4. Epub 2023 Feb 23. Bone Marrow Transplant. 2023. PMID: 36823455 Free PMC article. No abstract available.
Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol.
Toksvang LN, Als-Nielsen B, Bacon C, Bertasiute R, Duarte X, Escherich G, Helgadottir EA, Johannsdottir IR, Jónsson ÓG, Kozlowski P, Langenskjöld C, Lepik K, Niinimäki R, Overgaard UM, Punab M, Räty R, Segers H, van der Sluis I, Smith OP, Strullu M, Vaitkevičienė G, Wik HS, Heyman M, Schmiegelow K. Toksvang LN, et al. Among authors: smith op. BMC Cancer. 2022 May 2;22(1):483. doi: 10.1186/s12885-022-09522-3. BMC Cancer. 2022. PMID: 35501736 Free PMC article.
161 results