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Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer.
Chen DG, Xie J, Choi J, Ng RH, Zhang R, Li S, Edmark R, Zheng H, Solomon B, Campbell KM, Medina E, Ribas A, Khatri P, Lanier LL, Mease PJ, Goldman JD, Su Y, Heath JR. Chen DG, et al. Among authors: lanier ll. Cell Rep. 2024 Mar 26;43(3):113872. doi: 10.1016/j.celrep.2024.113872. Epub 2024 Feb 29. Cell Rep. 2024. PMID: 38427562 Free PMC article.
NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.
Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Lanier LL, Greenland JR, Sayah DM, Ardehali A, Kukreja J, Weigt SS, Belperio JA, Singer JP, Looney MR. Calabrese DR, et al. Among authors: lanier ll. JCI Insight. 2022 Dec 22;7(24):e164603. doi: 10.1172/jci.insight.164603. JCI Insight. 2022. PMID: 36346670 Free PMC article.
CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.
Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden JA, Leard L, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier LL, Looney MR, Greenland JR, Calabrese DR. Santos J, et al. Among authors: lanier ll. JCI Insight. 2023 Nov 8;8(21):e173716. doi: 10.1172/jci.insight.173716. JCI Insight. 2023. PMID: 37788115 Free PMC article.
MICB Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death.
Aguilar OA, Qualls AE, Gonzalez-Hinojosa MDR, Obeidalla S, Kerchberger VE, Tsao T, Singer JP, Looney MR, Raymond W, Hays SR, Golden JA, Kukreja J, Shaver CM, Ware LB, Christie J, Diamond JM, Lanier LL, Greenland JR, Calabrese DR. Aguilar OA, et al. Among authors: lanier ll. Am J Respir Crit Care Med. 2024 Jan 1;209(1):70-82. doi: 10.1164/rccm.202303-0472OC. Am J Respir Crit Care Med. 2024. PMID: 37878820
PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways.
Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R. Yang J, et al. Among authors: lanier ll. Cancer Immunol Res. 2024 May 2;12(5):575-591. doi: 10.1158/2326-6066.CIR-23-0722. Cancer Immunol Res. 2024. PMID: 38588410 Free PMC article.
ITAM-based receptors in natural killer cells.
Aguilar OA, Fong LK, Lanier LL. Aguilar OA, et al. Among authors: lanier ll. Immunol Rev. 2024 May;323(1):40-53. doi: 10.1111/imr.13313. Epub 2024 Feb 27. Immunol Rev. 2024. PMID: 38411263 Review.
Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.
Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis J, Hogrebe NJ, Gattis C, Basco R, Millman JR, Kievit P, Davis MM, Lanier LL, Connolly AJ, Deuse T, Schrepfer S. Hu X, et al. Among authors: lanier ll. Nat Biotechnol. 2024 Mar;42(3):413-423. doi: 10.1038/s41587-023-01784-x. Epub 2023 May 8. Nat Biotechnol. 2024. PMID: 37156915 Free PMC article.
487 results