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Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C. Abu-Hayyeh S, et al. Among authors: marschall hu. Hepatology. 2013 Feb;57(2):716-26. doi: 10.1002/hep.26055. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22961653 Free PMC article.
Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy.
Geenes V, Chambers J, Khurana R, Shemer EW, Sia W, Mandair D, Elias E, Marschall HU, Hague W, Williamson C. Geenes V, et al. Among authors: marschall hu. Eur J Obstet Gynecol Reprod Biol. 2015 Jun;189:59-63. doi: 10.1016/j.ejogrb.2015.03.020. Epub 2015 Mar 28. Eur J Obstet Gynecol Reprod Biol. 2015. PMID: 25864112
Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum.
Abu-Hayyeh S, Ovadia C, Lieu T, Jensen DD, Chambers J, Dixon PH, Lövgren-Sandblom A, Bolier R, Tolenaars D, Kremer AE, Syngelaki A, Noori M, Williams D, Marin JJ, Monte MJ, Nicolaides KH, Beuers U, Oude-Elferink R, Seed PT, Chappell L, Marschall HU, Bunnett NW, Williamson C. Abu-Hayyeh S, et al. Among authors: marschall hu. Hepatology. 2016 Apr;63(4):1287-98. doi: 10.1002/hep.28265. Epub 2015 Dec 28. Hepatology. 2016. PMID: 26426865 Free PMC article.
Role of Bile Acids in Metabolic Control.
Molinaro A, Wahlström A, Marschall HU. Molinaro A, et al. Among authors: marschall hu. Trends Endocrinol Metab. 2018 Jan;29(1):31-41. doi: 10.1016/j.tem.2017.11.002. Epub 2017 Nov 28. Trends Endocrinol Metab. 2018. PMID: 29195686 Review.
251 results