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Biochemical and Structural Studies of the Carminomycin 4-O-Methyltransferase DnrK.
Jalali E, Wang F, Overbay BR, Miller MD, Shaaban KA, Ponomareva LV, Ye Q, Saghaeiannejad-Esfahani H, Bhardwaj M, Steele AD, Teijaro CN, Shen B, Van Lanen SG, She QB, Voss SR, Phillips GN Jr, Thorson JS. Jalali E, et al. Among authors: bhardwaj m. J Nat Prod. 2024 Apr 26;87(4):798-809. doi: 10.1021/acs.jnatprod.3c00947. Epub 2024 Feb 27. J Nat Prod. 2024. PMID: 38412432
A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.
Bhardwaj M, Cui Z, Daniel Hankore E, Moonschi FH, Saghaeiannejad Esfahani H, Kalkreuter E, Gui C, Yang D, Phillips GN Jr, Thorson JS, Shen B, Van Lanen SG. Bhardwaj M, et al. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2220468120. doi: 10.1073/pnas.2220468120. Epub 2023 Feb 21. Proc Natl Acad Sci U S A. 2023. PMID: 36802426 Free PMC article.
Enzymatic Cβ-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases.
Cui Z, Nguyen H, Bhardwaj M, Wang X, Büschleb M, Lemke A, Schütz C, Rohrbacher C, Junghanns P, Koppermann S, Ducho C, Thorson JS, Van Lanen SG. Cui Z, et al. Among authors: bhardwaj m. J Am Chem Soc. 2021 Nov 24;143(46):19425-19437. doi: 10.1021/jacs.1c08177. Epub 2021 Nov 12. J Am Chem Soc. 2021. PMID: 34767710 Free PMC article.
Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions.
Pan J, Bhardwaj M, Zhang B, Chang WC, Schardl CL, Krebs C, Grossman RB, Bollinger JM Jr. Pan J, et al. Among authors: bhardwaj m. Biochemistry. 2018 Apr 10;57(14):2074-2083. doi: 10.1021/acs.biochem.8b00157. Epub 2018 Mar 29. Biochemistry. 2018. PMID: 29537853 Free PMC article.
440 results