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Safety and efficacy of autologous haematopoietic stem-cell transplantation with low-dose cyclophosphamide mobilisation and reduced intensity conditioning versus standard of care in refractory Crohn's disease (ASTIClite): an open-label, multicentre, randomised controlled trial.
Lancet Gastroenterol Hepatol. 2024 Apr;9(4):333-345. doi: 10.1016/S2468-1253(23)00460-0. Epub 2024 Feb 7.
Lancet Gastroenterol Hepatol. 2024.
PMID: 38340759
Free article.
Clinical Trial.
Autologous stem cell transplantation with low-dose cyclophosphamide to improve mucosal healing in adults with refractory Crohn’s disease: the ASTIClite RCT.
Lindsay JO, Hind D, Swaby L, Berntsson H, Bradburn M, Bannur C U, Byrne J, Clarke C, Desoysa L, Din S, Emsley R, Foulds GA, Gribben J, Hawkey C, Irving PM, Johnson P, Kazmi M, Lee E, Loban A, Lobo A, Mahida Y, Moran G, Papaioannou D, Parkes M, Peniket A, Pockley AG, Satsangi J, Subramanian S, Travis S, Turton E, Uttenthal B, Rutella S, Snowden JA.
Lindsay JO, et al. Among authors: bannur c u.
Southampton (UK): National Institute for Health and Care Research; 2024 Jan.
Southampton (UK): National Institute for Health and Care Research; 2024 Jan.
PMID: 38408175
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