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Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay.
Northcott J, Bartha G, Harris J, Li C, Navarro FCP, Pyke RM, Hong M, Zhang Q, Ma S, Chen TX, Lai J, Udar N, Saldivar JS, Ayash E, Anderson J, Li J, Cui T, Le T, Chow R, Velasco RJ, Mallo C, Santiago R, Bruce RC, Goodman LJ, Chen Y, Norton D, Chen RO, Lyle JM. Northcott J, et al. Among authors: pyke rm. Oncotarget. 2024 Mar 14;15:200-218. doi: 10.18632/oncotarget.28565. Oncotarget. 2024. PMID: 38484152 Free PMC article.
Withdrawal of 'Precision Neoantigen Discovery Using Large-scale Immunopeptidomes and Composite Modeling of MHC Peptide Presentation'.
Pyke RM, Mellacheruvu D, Dea S, Abbott CW, Zhang SV, Phillips NA, Harris J, Bartha G, Desai S, McClory R, West J, Snyder MP, Chen R, Boyle SM. Pyke RM, et al. Mol Cell Proteomics. 2023 Apr;22(4):100511. doi: 10.1016/j.mcpro.2023.100511. Epub 2023 Apr 3. Mol Cell Proteomics. 2023. PMID: 37019059 Free PMC article. No abstract available.
Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms.
Abbott CW, Boyle SM, Pyke RM, McDaniel LD, Levy E, Navarro FCP, Mellacheruvu D, Zhang SV, Tan M, Santiago R, Rusan ZM, Milani P, Bartha G, Harris J, McClory R, Snyder MP, Jang S, Chen R. Abbott CW, et al. Among authors: pyke rm. Clin Cancer Res. 2021 Aug 1;27(15):4265-4276. doi: 10.1158/1078-0432.CCR-20-4314. Clin Cancer Res. 2021. PMID: 34341053 Free PMC article.
Strength of immune selection in tumors varies with sex and age.
Castro A, Pyke RM, Zhang X, Thompson WK, Day CP, Alexandrov LB, Zanetti M, Carter H. Castro A, et al. Among authors: pyke rm. Nat Commun. 2020 Aug 17;11(1):4128. doi: 10.1038/s41467-020-17981-0. Nat Commun. 2020. PMID: 32807809 Free PMC article.
75 results