Wright GD - Search Results

1

Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity.

Puumala E, Sychantha D, Lach E, Reeves S, Nabeela S, Fogal M, Nigam A, Johnson JW, Aspuru-Guzik A, Shapiro RS, Uppuluri P, Kalyaanamoorthy S, Magolan J, Whitesell L, Robbins N, Wright GD, Cowen LE. Puumala E, et al. Among authors: wright gd. Cell Chem Biol. 2024 Apr 18;31(4):760-775.e17. doi: 10.1016/j.chembiol.2024.01.010. Epub 2024 Feb 22. Cell Chem Biol. 2024. PMID: 38402621 Free article.

2

An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens.

Robbins N, Spitzer M, Yu T, Cerone RP, Averette AK, Bahn YS, Heitman J, Sheppard DC, Tyers M, Wright GD. Robbins N, et al. Among authors: wright gd. Cell Rep. 2015 Nov 17;13(7):1481-1492. doi: 10.1016/j.celrep.2015.10.018. Epub 2015 Nov 5. Cell Rep. 2015. PMID: 26549450 Free PMC article.

3

Evolving medicinal chemistry strategies in antibiotic discovery.

Pawlowski AC, Johnson JW, Wright GD. Pawlowski AC, et al. Among authors: wright gd. Curr Opin Biotechnol. 2016 Dec;42:108-117. doi: 10.1016/j.copbio.2016.04.006. Epub 2016 Apr 24. Curr Opin Biotechnol. 2016. PMID: 27116217 Review.

4

Combinatorial strategies for combating invasive fungal infections.

Spitzer M, Robbins N, Wright GD. Spitzer M, et al. Among authors: wright gd. Virulence. 2017 Feb 17;8(2):169-185. doi: 10.1080/21505594.2016.1196300. Epub 2016 Jun 7. Virulence. 2017. PMID: 27268286 Free PMC article. Review.

5

Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function.

Robbins N, Spitzer M, Wang W, Waglechner N, Patel DJ, O'Brien JS, Ejim L, Ejim O, Tyers M, Wright GD. Robbins N, et al. Among authors: wright gd. Cell Chem Biol. 2016 Nov 17;23(11):1383-1394. doi: 10.1016/j.chembiol.2016.08.015. Epub 2016 Oct 13. Cell Chem Biol. 2016. PMID: 27746129 Free article.

6

Antifungal Drugs: The Current Armamentarium and Development of New Agents.

Robbins N, Wright GD, Cowen LE. Robbins N, et al. Among authors: wright gd. Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.FUNK-0002-2016. Microbiol Spectr. 2016. PMID: 27763259 Free article. Review.

7

Suppression of β-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-β-Lactamase Target and the Antibiotic Partner.

Rotondo CM, Sychantha D, Koteva K, Wright GD. Rotondo CM, et al. Among authors: wright gd. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e01386-19. doi: 10.1128/AAC.01386-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31932375 Free PMC article.

8

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling.

Culp EJ, Waglechner N, Wang W, Fiebig-Comyn AA, Hsu YP, Koteva K, Sychantha D, Coombes BK, Van Nieuwenhze MS, Brun YV, Wright GD. Culp EJ, et al. Among authors: wright gd. Nature. 2020 Feb;578(7796):582-587. doi: 10.1038/s41586-020-1990-9. Epub 2020 Feb 12. Nature. 2020. PMID: 32051588

9

Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.

Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, Russell J, Zouggar A, Masibag AN, Caba C, Koteva K, Kinthada LK, Patel JS, Andres SN, Magolan J, Collins TJ, Wright GD, Bhatia M. Benoit YD, et al. Among authors: wright gd. Cell Chem Biol. 2021 Oct 21;28(10):1394-1406.e10. doi: 10.1016/j.chembiol.2021.04.014. Epub 2021 May 11. Cell Chem Biol. 2021. PMID: 33979648 Free PMC article.

10

Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn².

Sychantha D, Rotondo CM, Tehrani KHME, Martin NI, Wright GD. Sychantha D, et al. Among authors: wright gd. J Biol Chem. 2021 Aug;297(2):100918. doi: 10.1016/j.jbc.2021.100918. Epub 2021 Jun 25. J Biol Chem. 2021. PMID: 34181945 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

394 results

Search Page