Koeberle A - Search Results

1

Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans.

Sharifi S, Chaudhari P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M. Sharifi S, et al. Among authors: koeberle a. Nat Commun. 2024 Feb 24;15(1):1702. doi: 10.1038/s41467-024-46037-w. Nat Commun. 2024. PMID: 38402241 Free PMC article.

2

Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans.

Espada L, Dakhovnik A, Chaudhari P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Döring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA. Espada L, et al. Among authors: koeberle a. Nat Metab. 2020 Nov;2(11):1316-1331. doi: 10.1038/s42255-020-00307-1. Epub 2020 Nov 2. Nat Metab. 2020. PMID: 33139960

3

Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders.

Koeberle A, Werz O. Koeberle A, et al. Biochem Pharmacol. 2015 Nov 1;98(1):1-15. doi: 10.1016/j.bcp.2015.06.022. Epub 2015 Jun 27. Biochem Pharmacol. 2015. PMID: 26123522 Review.

4

Natural products as inhibitors of prostaglandin E₂ and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis.

Koeberle A, Werz O. Koeberle A, et al. Biotechnol Adv. 2018 Nov 1;36(6):1709-1723. doi: 10.1016/j.biotechadv.2018.02.010. Epub 2018 Feb 15. Biotechnol Adv. 2018. PMID: 29454981 Review.

5

Multi-target approach for natural products in inflammation.

Koeberle A, Werz O. Koeberle A, et al. Drug Discov Today. 2014 Dec;19(12):1871-82. doi: 10.1016/j.drudis.2014.08.006. Epub 2014 Aug 27. Drug Discov Today. 2014. PMID: 25172801 Review.

6

PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.

Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A. Thürmer M, et al. Among authors: koeberle a. Nat Commun. 2022 May 27;13(1):2982. doi: 10.1038/s41467-022-30374-9. Nat Commun. 2022. PMID: 35624087 Free PMC article.

7

Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis.

Deb S, Felix DA, Koch P, Deb MK, Szafranski K, Buder K, Sannai M, Groth M, Kirkpatrick J, Pietsch S, Gollowitzer A, Groß A, Riemenschneider P, Koeberle A, González-Estévez C, Rudolph KL. Deb S, et al. Among authors: koeberle a. EMBO Rep. 2021 Jan 7;22(1):e49328. doi: 10.15252/embr.201949328. Epub 2020 Dec 10. EMBO Rep. 2021. PMID: 33300287 Free PMC article.

8

α-Tocopherol-13'-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation.

Liao S, Gollowitzer A, Börmel L, Maier C, Gottschalk L, Werz O, Wallert M, Koeberle A, Lorkowski S. Liao S, et al. Among authors: koeberle a. Int J Mol Sci. 2023 May 25;24(11):9229. doi: 10.3390/ijms24119229. Int J Mol Sci. 2023. PMID: 37298183 Free PMC article.

9

Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions.

Koeberle A, Laufer SA, Werz O. Koeberle A, et al. J Med Chem. 2016 Jul 14;59(13):5970-86. doi: 10.1021/acs.jmedchem.5b01750. Epub 2016 Feb 24. J Med Chem. 2016. PMID: 26791385

10

Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms.

Koeberle SC, Gollowitzer A, Laoukili J, Kranenburg O, Werz O, Koeberle A, Kipp AP. Koeberle SC, et al. Among authors: koeberle a. Redox Biol. 2020 Jan;28:101388. doi: 10.1016/j.redox.2019.101388. Epub 2019 Nov 16. Redox Biol. 2020. PMID: 31765890 Free PMC article.

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