El-Kattan AF - Search Results

1

In situ evaluation of the impact of metformin or verapamil coadministration with vildagliptin on its regional absorption from the rabbit's intestine.

Elmeniar AM, Osman MA, El-Gizawy SA, Modi D, Charbe NB, El-Kattan AF, El-Tanani M, Haggag YA, Tambuwala MM. Elmeniar AM, et al. Among authors: el kattan af. Biopharm Drug Dispos. 2024 Apr;45(2):71-82. doi: 10.1002/bdd.2384. Epub 2024 Feb 24. Biopharm Drug Dispos. 2024. PMID: 38400763

2

Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models.

Jiménez de Oya N, Esler WP, Huard K, El-Kattan AF, Karamanlidis G, Blázquez AB, Ramos-Ibeas P, Escribano-Romero E, Louloudes-Lázaro A, Casas J, Sobrino F, Hoehn K, James DE, Gutiérrez-Adán A, Saiz JC, Martín-Acebes MA. Jiménez de Oya N, et al. Among authors: el kattan af. Emerg Microbes Infect. 2019;8(1):624-636. doi: 10.1080/22221751.2019.1604084. Emerg Microbes Infect. 2019. PMID: 30999821 Free PMC article.

3

2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety.

Dow RL, Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Cortes C, El-Kattan AF, Ford K, Freeman GB, Guimarães CRW, Liu S, Niosi M, Skoura A, Tess D. Dow RL, et al. Among authors: el kattan af. J Med Chem. 2018 Apr 12;61(7):3114-3125. doi: 10.1021/acs.jmedchem.8b00152. Epub 2018 Apr 3. J Med Chem. 2018. PMID: 29570292

4

Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System.

El-Kattan AF, Varma MVS. El-Kattan AF, et al. Drug Metab Dispos. 2018 May;46(5):729-739. doi: 10.1124/dmd.117.080044. Epub 2018 Mar 1. Drug Metab Dispos. 2018. PMID: 29496721 Review.

5

A Study on Pharmacokinetics of Bosentan with Systems Modeling, Part 1: Translating Systemic Plasma Concentration to Liver Exposure in Healthy Subjects.

Li R, Niosi M, Johnson N, Tess DA, Kimoto E, Lin J, Yang X, Riccardi KA, Ryu S, El-Kattan AF, Maurer TS, Tremaine LM, Di L. Li R, et al. Among authors: el kattan af. Drug Metab Dispos. 2018 Apr;46(4):346-356. doi: 10.1124/dmd.117.078790. Epub 2018 Jan 12. Drug Metab Dispos. 2018. PMID: 29330218

6

Molecular properties associated with transporter-mediated drug disposition.

Varma MV, Lai Y, El-Kattan AF. Varma MV, et al. Among authors: el kattan af. Adv Drug Deliv Rev. 2017 Jul 1;116:92-99. doi: 10.1016/j.addr.2017.05.014. Epub 2017 May 26. Adv Drug Deliv Rev. 2017. PMID: 28554577 Review.

7

Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters.

Varma MV, El-Kattan AF, Feng B, Steyn SJ, Maurer TS, Scott DO, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: el kattan af. Clin Pharmacol Ther. 2017 Jul;102(1):33-36. doi: 10.1002/cpt.595. Epub 2017 Feb 3. Clin Pharmacol Ther. 2017. PMID: 27984654 No abstract available.

8

Projecting ADME Behavior and Drug-Drug Interactions in Early Discovery and Development: Application of the Extended Clearance Classification System.

El-Kattan AF, Varma MV, Steyn SJ, Scott DO, Maurer TS, Bergman A. El-Kattan AF, et al. Pharm Res. 2016 Dec;33(12):3021-3030. doi: 10.1007/s11095-016-2024-z. Epub 2016 Sep 12. Pharm Res. 2016. PMID: 27620173

9

Transporter-Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug-Drug Interactions of Montelukast.

Varma MV, Kimoto E, Scialis R, Bi Y, Lin J, Eng H, Kalgutkar AS, El-Kattan AF, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: el kattan af. Clin Pharmacol Ther. 2017 Mar;101(3):406-415. doi: 10.1002/cpt.520. Epub 2016 Nov 18. Clin Pharmacol Ther. 2017. PMID: 27648490

10

Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion: From the Bench to the Bedside - Clinical Pharmacology Considerations.

Ronaldson PT, Bauer B, El-Kattan AF, Shen H, Salphati L, Louie SW. Ronaldson PT, et al. Among authors: el kattan af. Clin Pharmacol Ther. 2016 Nov;100(5):419-422. doi: 10.1002/cpt.439. Epub 2016 Sep 13. Clin Pharmacol Ther. 2016. PMID: 27500791 Free PMC article.

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