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Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra).
Barros ALAN, Silva VC, Ribeiro-Junior AF, Cardoso MG, Costa SR, Moraes CB, Barbosa CG, Coleone AP, Simões RP, Cabral WF, Falcão RM, Vasconcelos AG, Rocha JA, Arcanjo DDR, Batagin-Neto A, Borges TKS, Gonçalves J, Brand GD, Freitas-Junior LHG, Eaton P, Marani M, Kato MJ, Plácido A, Leite JRSA. Barros ALAN, et al. Among authors: rocha ja. Pharmaceutics. 2024 Jan 29;16(2):190. doi: 10.3390/pharmaceutics16020190. Pharmaceutics. 2024. PMID: 38399250 Free PMC article.
Structure⁻Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells.
Campelo Y, Ombredane A, Vasconcelos AG, Albuquerque L, Moreira DC, Plácido A, Rocha J, Hilarion Fokoue H, Yamaguchi L, Mafud A, Mascarenhas YP, Delerue-Matos C, Borges T, Joanitti GA, Arcanjo D, Kato MJ, Kuckelhaus SAS, Silva MPN, Moraes J, Leite JRSA. Campelo Y, et al. Int J Mol Sci. 2018 Jun 19;19(6):1802. doi: 10.3390/ijms19061802. Int J Mol Sci. 2018. PMID: 29921756 Free PMC article.
BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects.
de Sousa NA, Marani MM, Lopes ALF, Silva EM, Barbosa EA, Vasconcelos AG, Kuzniewski FTB, Lustosa SS, Gomes KP, Colugnati DB, Rocha JA, Santos LH, Benquerer MP, Quelemes P, Véras L, Moreira DC, Gadelha KKL, Magalhães PJC, Plácido A, Eaton P, Nicolau L, Medeiros JVR, Leite JRSA. de Sousa NA, et al. Among authors: rocha ja. Amino Acids. 2022 May;54(5):733-747. doi: 10.1007/s00726-021-03114-4. Epub 2022 Mar 13. Amino Acids. 2022. PMID: 35279763
Identification of Phenolic Compounds and Evaluation of Antioxidant and Antimicrobial Properties of Euphorbia Tirucalli L.
de Araújo KM, de Lima A, Silva Jdo N, Rodrigues LL, Amorim AG, Quelemes PV, Dos Santos RC, Rocha JA, de Andrades ÉO, Leite JR, Mancini-Filho J, da Trindade RA. de Araújo KM, et al. Among authors: rocha ja. Antioxidants (Basel). 2014 Mar 17;3(1):159-75. doi: 10.3390/antiox3010159. Antioxidants (Basel). 2014. PMID: 26784670 Free PMC article.
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches.
Santos ES, Silva PC, Sousa PSA, Aquino CC, Pacheco G, Teixeira LFLS, Araujo AR, Sousa FBM, Barros RO, Ramos RM, Rocha JA, Nicolau LAD, Medeiros JVR. Santos ES, et al. Among authors: rocha ja. Chem Biol Interact. 2022 Nov 1;367:110161. doi: 10.1016/j.cbi.2022.110161. Epub 2022 Sep 15. Chem Biol Interact. 2022. PMID: 36116513 Free PMC article.
SARS-CoV-2 Spike protein triggers gut impairment since mucosal barrier to innermost layers: From basic science to clinical relevance.
Nascimento RR, Aquino CC, Sousa JK, Gadelha KL, Cajado AG, Schiebel CS, Dooley SA, Sousa PA, Rocha JA, Medeiros JR, Magalhães PC, Maria-Ferreira D, Gois MB, C P Lima-Junior R, V T Wong D, Lima AM, Engevik AC, Nicolau LD, Vale ML. Nascimento RR, et al. Among authors: rocha ja. Mucosal Immunol. 2024 Mar 29:S1933-0219(24)00029-1. doi: 10.1016/j.mucimm.2024.03.009. Online ahead of print. Mucosal Immunol. 2024. PMID: 38555027 Free article.
Synthetic hydrazones: In silico studies and in vitro evaluation of the antileishmania potential.
de Sousa VC, de Cássia Viana Carvalho R, Dos Reis Barcelar KG, de Melo DS, Nunes JM, de Araújo Sousa PS, Rocha JA, Lima CC, de Assis Gonsalves A, Araújo CRM, da Costa MP, da Franca Rodrigues KA, de Moraes Alves MM, de Amorim Carvalho FA. de Sousa VC, et al. Among authors: rocha ja. Toxicol In Vitro. 2023 Apr;88:105560. doi: 10.1016/j.tiv.2023.105560. Epub 2023 Jan 18. Toxicol In Vitro. 2023. PMID: 36681287
Antileishmanial activity of Riparin structural analogs of Aniba riparia: Biological evaluation, in silico Adme-Tox, and molecular docking.
Figueiredo KA, Magalhães Costa RK, Rocha JA, Chavez Gutierrez SJ, Ramos RM, Muálem de Moraes Alves M, Aécio de Amorim Carvalho F, Menezes Carvalho AL, Lima FDCA. Figueiredo KA, et al. Among authors: rocha ja. Exp Parasitol. 2022 May-Jun;236-237:108257. doi: 10.1016/j.exppara.2022.108257. Epub 2022 Apr 6. Exp Parasitol. 2022. PMID: 35398101
100 results