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Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra).
Barros ALAN, Silva VC, Ribeiro-Junior AF, Cardoso MG, Costa SR, Moraes CB, Barbosa CG, Coleone AP, Simões RP, Cabral WF, Falcão RM, Vasconcelos AG, Rocha JA, Arcanjo DDR, Batagin-Neto A, Borges TKS, Gonçalves J, Brand GD, Freitas-Junior LHG, Eaton P, Marani M, Kato MJ, Plácido A, Leite JRSA. Barros ALAN, et al. Among authors: leite jrsa. Pharmaceutics. 2024 Jan 29;16(2):190. doi: 10.3390/pharmaceutics16020190. Pharmaceutics. 2024. PMID: 38399250 Free PMC article.
The Antioxidant Peptide Salamandrin-I: First Bioactive Peptide Identified from Skin Secretion of Salamandra Genus (Salamandra salamandra).
Plácido A, Bueno J, Barbosa EA, Moreira DC, Dias JDN, Cabral WF, Albuquerque P, Bessa LJ, Freitas J, Kuckelhaus SAS, Lima FCDA, Batagin-Neto A, Brand GD, Relvas JB, Leite JRSA, Eaton P. Plácido A, et al. Among authors: leite jrsa. Biomolecules. 2020 Mar 27;10(4):512. doi: 10.3390/biom10040512. Biomolecules. 2020. PMID: 32230960 Free PMC article.
Structure⁻Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells.
Campelo Y, Ombredane A, Vasconcelos AG, Albuquerque L, Moreira DC, Plácido A, Rocha J, Hilarion Fokoue H, Yamaguchi L, Mafud A, Mascarenhas YP, Delerue-Matos C, Borges T, Joanitti GA, Arcanjo D, Kato MJ, Kuckelhaus SAS, Silva MPN, Moraes J, Leite JRSA. Campelo Y, et al. Among authors: leite jrsa. Int J Mol Sci. 2018 Jun 19;19(6):1802. doi: 10.3390/ijms19061802. Int J Mol Sci. 2018. PMID: 29921756 Free PMC article.
The peptide secreted at the water to land transition in a model amphibian has antioxidant effects.
Barbosa EA, Plácido A, Moreira DC, Albuquerque L, Dematei A, Silva-Carvalho AÉ, Cabral WF, Báo SN, Saldanha-Araújo F, Kuckelhaus SAS, Borges TK, Portugal CC, Socodato R, Teixeira C, Lima FCDA, Batagin-Neto A, Sebben A, Eaton P, Gomes P, Brand GD, Relvas JB, Kato MJ, Leite JRSA. Barbosa EA, et al. Among authors: leite jrsa. Proc Biol Sci. 2021 Nov 10;288(1962):20211531. doi: 10.1098/rspb.2021.1531. Epub 2021 Nov 10. Proc Biol Sci. 2021. PMID: 34753356 Free PMC article.
The Arsenal of Bioactive Molecules in the Skin Secretion of Urodele Amphibians.
Barros ALAN, Hamed A, Marani M, Moreira DC, Eaton P, Plácido A, Kato MJ, Leite JRSA. Barros ALAN, et al. Among authors: leite jrsa. Front Pharmacol. 2022 Jan 14;12:810821. doi: 10.3389/fphar.2021.810821. eCollection 2021. Front Pharmacol. 2022. PMID: 35095522 Free PMC article. Review.
Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni).
Dematei A, Costa SR, Moreira DC, Barbosa EA, Friaça Albuquerque LF, Vasconcelos AG, Nascimento T, Silva PC, Silva-Carvalho AÉ, Saldanha-Araújo F, Silva Mancini MC, Saboia Ponte LG, Neves Bezerra RM, Simabuco FM, Batagin-Neto A, Brand G, Borges TKS, Eaton P, Leite JRSA. Dematei A, et al. Among authors: leite jrsa. J Nat Prod. 2022 Dec 23;85(12):2695-2705. doi: 10.1021/acs.jnatprod.2c00304. Epub 2022 Dec 12. J Nat Prod. 2022. PMID: 36508333
Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme.
Arcanjo DDR, Vasconcelos AG, Nascimento LA, Mafud AC, Plácido A, Alves MMM, Delerue-Matos C, Bemquerer MP, Vale N, Gomes P, Oliveira EB, Lima FCA, Mascarenhas YP, Carvalho FAA, Simonsen U, Ramos RM, Leite JRSA. Arcanjo DDR, et al. Among authors: leite jrsa. Eur J Med Chem. 2017 Oct 20;139:401-411. doi: 10.1016/j.ejmech.2017.08.019. Epub 2017 Aug 7. Eur J Med Chem. 2017. PMID: 28810191
92 results