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Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
Tonelli M, Catto M, Sabaté R, Francesconi V, Laurini E, Pricl S, Pisani L, Miniero DV, Liuzzi GM, Gatta E, Relini A, Gavín R, Del Rio JA, Sparatore F, Carotti A. Tonelli M, et al. Among authors: miniero dv. Eur J Med Chem. 2023 Mar 15;250:115169. doi: 10.1016/j.ejmech.2023.115169. Epub 2023 Feb 2. Eur J Med Chem. 2023. PMID: 36753881 Free article.
Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.
Rullo M, La Spada G, Miniero DV, Gottinger A, Catto M, Delre P, Mastromarino M, Latronico T, Marchese S, Mangiatordi GF, Binda C, Linusson A, Liuzzi GM, Pisani L. Rullo M, et al. Among authors: miniero dv. Eur J Med Chem. 2023 Jul 5;255:115352. doi: 10.1016/j.ejmech.2023.115352. Epub 2023 Apr 8. Eur J Med Chem. 2023. PMID: 37178666
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity.
Al-Saad OM, Gabr M, Darwish SS, Rullo M, Pisani L, Miniero DV, Liuzzi GM, Kany AM, Hirsch AKH, Abadi AH, Engel M, Catto M, Abdel-Halim M. Al-Saad OM, et al. Among authors: miniero dv. Eur J Med Chem. 2024 Apr 5;269:116266. doi: 10.1016/j.ejmech.2024.116266. Epub 2024 Feb 28. Eur J Med Chem. 2024. PMID: 38490063 Free article.
Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization.
La Spada G, Miniero DV, Rullo M, Cipolloni M, Delre P, Colliva C, Colella M, Leonetti F, Liuzzi GM, Mangiatordi GF, Giacchè N, Pisani L. La Spada G, et al. Among authors: miniero dv. Eur J Med Chem. 2024 May 19;274:116511. doi: 10.1016/j.ejmech.2024.116511. Online ahead of print. Eur J Med Chem. 2024. PMID: 38820854 Free article.
Editorial: Understanding membrane transporters: from structure to function.
Pasquadibisceglie A, Bonaccorsi Di Patti MC, Miniero DV, Musci G, Polticelli F. Pasquadibisceglie A, et al. Among authors: miniero dv. Front Mol Biosci. 2023 Oct 30;10:1323824. doi: 10.3389/fmolb.2023.1323824. eCollection 2023. Front Mol Biosci. 2023. PMID: 38028551 Free PMC article. No abstract available.
Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults.
Samarelli F, Purgatorio R, Lopopolo G, Deruvo C, Catto M, Andresini M, Carrieri A, Nicolotti O, De Palma A, Miniero DV, de Candia M, Altomare CD. Samarelli F, et al. Among authors: miniero dv. Eur J Med Chem. 2024 Apr 15;270:116353. doi: 10.1016/j.ejmech.2024.116353. Epub 2024 Mar 20. Eur J Med Chem. 2024. PMID: 38579622 Free article.
31 results