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Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.
Wehrli M, Guinn S, Birocchi F, Kuo A, Sun Y, Larson RC, Almazan AJ, Scarfò I, Bouffard AA, Bailey SR, Anekal PV, Montero Llopis P, Nieman LT, Song Y, Xu KH, Berger TR, Kann MC, Leick MB, Silva H, Salas-Benito D, Kienka T, Grauwet K, Armstrong TD, Zhang R, Zhu Q, Fu J, Schmidts A, Korell F, Jan M, Choi BD, Liss AS, Boland GM, Ting DT, Burkhart RA, Jenkins RW, Zheng L, Jaffee EM, Zimmerman JW, Maus MV. Wehrli M, et al. Among authors: schmidts a. Clin Cancer Res. 2024 May 1;30(9):1859-1877. doi: 10.1158/1078-0432.CCR-23-3841. Clin Cancer Res. 2024. PMID: 38393682
Peritransplant CAR-T cells.
Schmidts A. Schmidts A. Blood. 2023 Feb 9;141(6):564-566. doi: 10.1182/blood.2022018584. Blood. 2023. PMID: 36757730 Free article. No abstract available.
The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.
Yalcin A, Kovarbasic M, Wehrle J, Claus R, Becker H, Abdelkarim M, Gaidzik VI, Schmidts A, Wäsch R, Pahl HL, Döhner K, Bullinger L, Duyster J, Lübbert M, Hackanson B. Yalcin A, et al. Among authors: schmidts a. Exp Hematol. 2017 Nov;55:76-85.e3. doi: 10.1016/j.exphem.2017.07.009. Epub 2017 Jul 28. Exp Hematol. 2017. PMID: 28760688 Free article.
A gentler yield of ex vivo-edited T cells.
Grünewald J, Schmidts A. Grünewald J, et al. Among authors: schmidts a. Nat Biomed Eng. 2023 May;7(5):607-608. doi: 10.1038/s41551-023-01042-0. Nat Biomed Eng. 2023. PMID: 37208465 No abstract available.
Making CAR T Cells a Solid Option for Solid Tumors.
Schmidts A, Maus MV. Schmidts A, et al. Front Immunol. 2018 Nov 8;9:2593. doi: 10.3389/fimmu.2018.02593. eCollection 2018. Front Immunol. 2018. PMID: 30467505 Free PMC article. Review.
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity.
Choi BD, Yu X, Castano AP, Bouffard AA, Schmidts A, Larson RC, Bailey SR, Boroughs AC, Frigault MJ, Leick MB, Scarfò I, Cetrulo CL, Demehri S, Nahed BV, Cahill DP, Wakimoto H, Curry WT, Carter BS, Maus MV. Choi BD, et al. Among authors: schmidts a. Nat Biotechnol. 2019 Sep;37(9):1049-1058. doi: 10.1038/s41587-019-0192-1. Epub 2019 Jul 22. Nat Biotechnol. 2019. PMID: 31332324
31 results