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Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Gerhart JG, Carreño FO, Ford JL, Edginton AN, Perrin EM, Watt KM, Muller WJ, Atz AM, Al-Uzri A, Delmore P, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Gerhart JG, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):778-791. doi: 10.1002/psp4.12793. Epub 2022 May 2. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35491971 Free PMC article.
Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity.
Gerhart JG, Carreño FO, Loop MS, Lee CR, Edginton AN, Sinha J, Kumar KR, Kirkpatrick CM, Hornik CP, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Gerhart JG, et al. Clin Pharmacol Ther. 2022 Aug;112(2):391-403. doi: 10.1002/cpt.2618. Epub 2022 May 18. Clin Pharmacol Ther. 2022. PMID: 35451072 Free PMC article.
Utility of the 13 C-pantoprazole breath test as a CYP2C19 phenotyping probe for children.
Feldman K, Kearns GL, Pearce RE, Abdel-Rahman SM, Steven Leeder J, Friesen A, Staggs VS, Gaedigk A, Weigel J, Shakhnovich V. Feldman K, et al. Among authors: kearns gl. Clin Transl Sci. 2022 May;15(5):1155-1166. doi: 10.1111/cts.13232. Epub 2022 Feb 14. Clin Transl Sci. 2022. PMID: 35099109 Free PMC article. Clinical Trial.
Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Gerhart JG, Carreño FO, Edginton AN, Sinha J, Perrin EM, Kumar KR, Rikhi A, Hornik CP, Harris V, Ganguly S, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Gerhart JG, et al. Clin Pharmacokinet. 2022 Feb;61(2):307-320. doi: 10.1007/s40262-021-01072-4. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617262 Free PMC article.
Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity.
Maharaj AR, Wu H, Zimmerman KO, Muller WJ, Sullivan JE, Sherwin CMT, Autmizguine J, Rathore MH, Hornik CD, Al-Uzri A, Payne EH, Benjamin DK Jr, Hornik CP; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Maharaj AR, et al. Paediatr Drugs. 2021 Sep;23(5):499-513. doi: 10.1007/s40272-021-00460-4. Epub 2021 Jul 23. Paediatr Drugs. 2021. PMID: 34302290 Free PMC article.
Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.
Ganguly S, Edginton AN, Gerhart JG, Cohen-Wolkowiez M, Greenberg RG, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Ganguly S, et al. Clin Pharmacokinet. 2021 Dec;60(12):1591-1604. doi: 10.1007/s40262-021-01046-6. Epub 2021 Jun 22. Clin Pharmacokinet. 2021. PMID: 34155614 Free PMC article.
Clearance of buprenorphine during pregnancy and neonatal outcomes.
Coker JL, Ray-Griffith SL, McLeod C, Han X, Mancino M, Kearns GL, Stowe ZN. Coker JL, et al. Among authors: kearns gl. Arch Womens Ment Health. 2021 Dec;24(6):933-939. doi: 10.1007/s00737-021-01128-1. Epub 2021 Apr 16. Arch Womens Ment Health. 2021. PMID: 33864131
314 results