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Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.
Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Györke S. Brunello L, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10312-7. doi: 10.1073/pnas.1300052110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733959 Free PMC article.
SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Musa H, Kline CF, Sturm AC, Murphy N, Adelman S, Wang C, Yan H, Johnson BL, Csepe TA, Kilic A, Higgins RS, Janssen PM, Fedorov VV, Weiss R, Salazar C, Hund TJ, Pitt GS, Mohler PJ. Musa H, et al. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12528-33. doi: 10.1073/pnas.1516430112. Epub 2015 Sep 21. Proc Natl Acad Sci U S A. 2015. PMID: 26392562 Free PMC article.
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility.
Lynch TL 4th, Kumar M, McNamara JW, Kuster DWD, Sivaguru M, Singh RR, Previs MJ, Lee KH, Kuffel G, Zilliox MJ, Lin BL, Ma W, Gibson AM, Blaxall BC, Nieman ML, Lorenz JN, Leichter DM, Leary OP, Janssen PML, de Tombe PP, Gilbert RJ, Craig R, Irving T, Warshaw DM, Sadayappan S. Lynch TL 4th, et al. Among authors: janssen pml. J Mol Cell Cardiol. 2021 Jul;156:33-44. doi: 10.1016/j.yjmcc.2021.03.009. Epub 2021 Mar 26. J Mol Cell Cardiol. 2021. PMID: 33781820 Free PMC article.
Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.
Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ. Nixon BR, et al. Arch Biochem Biophys. 2013 Jul 1;535(1):30-8. doi: 10.1016/j.abb.2012.11.010. Epub 2012 Dec 8. Arch Biochem Biophys. 2013. PMID: 23232082 Free PMC article.
213 results