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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Liu F, Ryan ST, Fahnoe KC, Morgan JG, Cheung AE, Storek MJ, Best A, Chen HA, Locatelli M, Xu S, Schmidt E, Schmidt-Jiménez LF, Bieber K, Henderson JM, Lian CG, Verschoor A, Ludwig RJ, Benigni A, Remuzzi G, Salant DJ, Kalled SL, Thurman JM, Holers VM, Violette SM, Wawersik S. Liu F, et al. Among authors: remuzzi g. Mol Ther. 2024 Apr 3;32(4):1061-1079. doi: 10.1016/j.ymthe.2024.02.001. Epub 2024 Feb 20. Mol Ther. 2024. PMID: 38382529 Free article.
SARS-CoV-2 and the spike protein in endotheliopathy.
Perico L, Benigni A, Remuzzi G. Perico L, et al. Among authors: remuzzi g. Trends Microbiol. 2024 Jan;32(1):53-67. doi: 10.1016/j.tim.2023.06.004. Epub 2023 Jun 12. Trends Microbiol. 2024. PMID: 37393180 Free PMC article. Review.
Efficacy of GalNAc C3 siRNAs in factor H-deficient mice with C3 glomerulopathy.
Zanchi C, Locatelli M, Cerullo D, Aumiller V, Corna D, Rottoli D, Schubert S, Noris M, Tomasoni S, Remuzzi G, Zoja C, Benigni A. Zanchi C, et al. Among authors: remuzzi g. Mol Immunol. 2024 Apr;168:10-16. doi: 10.1016/j.molimm.2024.02.010. Epub 2024 Feb 17. Mol Immunol. 2024. PMID: 38368725 Free article.
1,515 results