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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Mol Ther. 2024 Apr 3;32(4):1061-1079. doi: 10.1016/j.ymthe.2024.02.001. Epub 2024 Feb 20.
Mol Ther. 2024.
PMID: 38382529
Free article.
Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Fahnoe KC, Liu F, Morgan JG, Ryan ST, Storek M, Stark EG, Taylor FR, Holers VM, Thurman JM, Wawersik S, Kalled SL, Violette SM.
Fahnoe KC, et al.
Front Immunol. 2022 Jun 16;13:869725. doi: 10.3389/fimmu.2022.869725. eCollection 2022.
Front Immunol. 2022.
PMID: 35784298
Free PMC article.
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Non-traditional antibacterial screening approaches for the identification of novel inhibitors of the glyoxylate shunt in gram-negative pathogens.
Fahnoe KC, Flanagan ME, Gibson G, Shanmugasundaram V, Che Y, Tomaras AP.
Fahnoe KC, et al.
PLoS One. 2012;7(12):e51732. doi: 10.1371/journal.pone.0051732. Epub 2012 Dec 11.
PLoS One. 2012.
PMID: 23240059
Free PMC article.
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Clinically relevant Gram-negative resistance mechanisms have no effect on the efficacy of MC-1, a novel siderophore-conjugated monocarbam.
McPherson CJ, Aschenbrenner LM, Lacey BM, Fahnoe KC, Lemmon MM, Finegan SM, Tadakamalla B, O'Donnell JP, Mueller JP, Tomaras AP.
McPherson CJ, et al. Among authors: fahnoe kc.
Antimicrob Agents Chemother. 2012 Dec;56(12):6334-42. doi: 10.1128/AAC.01345-12. Epub 2012 Oct 1.
Antimicrob Agents Chemother. 2012.
PMID: 23027195
Free PMC article.
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