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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Mol Ther. 2024 Apr 3;32(4):1061-1079. doi: 10.1016/j.ymthe.2024.02.001. Epub 2024 Feb 20.
Mol Ther. 2024.
PMID: 38382529
Free article.
A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants.
Schenkel LB, Molina JR, Swinger KK, Abo R, Blackwell DJ, Lu AZ, Cheung AE, Church WD, Kunii K, Kuplast-Barr KG, Majer CR, Minissale E, Mo JR, Niepel M, Reik C, Ren Y, Vasbinder MM, Wigle TJ, Richon VM, Keilhack H, Kuntz KW.
Schenkel LB, et al. Among authors: cheung ae.
Cell Chem Biol. 2021 Aug 19;28(8):1158-1168.e13. doi: 10.1016/j.chembiol.2021.02.010. Epub 2021 Mar 10.
Cell Chem Biol. 2021.
PMID: 33705687
Free article.
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Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration.
Wang Q, Delva L, Weinreb PH, Pepinsky RB, Graham D, Veizaj E, Cheung AE, Chen W, Nestorov I, Rohde E, Caputo R, Kuesters GM, Bohnert T, Gan LS.
Wang Q, et al. Among authors: cheung ae.
Fluids Barriers CNS. 2018 Mar 20;15(1):10. doi: 10.1186/s12987-018-0093-6.
Fluids Barriers CNS. 2018.
PMID: 29558954
Free PMC article.
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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, Dunah AW, Wittmann M, Bussiere T, Weinreb PH, Hyman BT, Takeda S.
Nobuhara CK, et al. Among authors: cheung ae.
Am J Pathol. 2017 Jun;187(6):1399-1412. doi: 10.1016/j.ajpath.2017.01.022. Epub 2017 Apr 11.
Am J Pathol. 2017.
PMID: 28408124
Free PMC article.
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An antibody-cytotoxic conjugate, BIIB015, is a new targeted therapy for Cripto positive tumours.
Kelly RK, Olson DL, Sun Y, Wen D, Wortham KA, Antognetti G, Cheung AE, Orozco OE, Yang L, Bailly V, Sanicola M.
Kelly RK, et al. Among authors: cheung ae.
Eur J Cancer. 2011 Jul;47(11):1736-46. doi: 10.1016/j.ejca.2011.02.023. Epub 2011 Mar 31.
Eur J Cancer. 2011.
PMID: 21458984
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Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
Adkins HB, Bianco C, Schiffer SG, Rayhorn P, Zafari M, Cheung AE, Orozco O, Olson D, De Luca A, Chen LL, Miatkowski K, Benjamin C, Normanno N, Williams KP, Jarpe M, LePage D, Salomon D, Sanicola M.
Adkins HB, et al. Among authors: cheung ae.
J Clin Invest. 2003 Aug;112(4):575-87. doi: 10.1172/JCI17788.
J Clin Invest. 2003.
PMID: 12925698
Free PMC article.
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The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto. Functional and structural insights through disulfide structure analysis.
Foley SF, van Vlijmen HW, Boynton RE, Adkins HB, Cheung AE, Singh J, Sanicola M, Young CN, Wen D.
Foley SF, et al. Among authors: cheung ae.
Eur J Biochem. 2003 Sep;270(17):3610-8. doi: 10.1046/j.1432-1033.2003.03749.x.
Eur J Biochem. 2003.
PMID: 12919325
Free article.
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