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A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility.
Morgan PK, Pernes G, Huynh K, Giles C, Paul S, Smith AAT, Mellett NA, Liang A, van Buuren-Milne T, Veiga CB, Collins TJC, Xu Y, Lee MKS, De Silva TM, Meikle PJ, Lancaster GI, Murphy AJ. Morgan PK, et al. Among authors: mellett na. Nat Cell Biol. 2024 Apr;26(4):645-659. doi: 10.1038/s41556-024-01377-z. Epub 2024 Apr 8. Nat Cell Biol. 2024. PMID: 38589531
Imputation of plasma lipid species to facilitate integration of lipidomic datasets.
Dakic A, Wu J, Wang T, Huynh K, Mellett N, Duong T, Beyene HB, Magliano DJ, Shaw JE, Carrington MJ, Inouye M, Yang JY, Figtree GA, Curran JE, Blangero J, Simes J; LIPID Study Investigators; Giles C, Meikle PJ. Dakic A, et al. Among authors: mellett n. Nat Commun. 2024 Feb 20;15(1):1540. doi: 10.1038/s41467-024-45838-3. Nat Commun. 2024. PMID: 38378775 Free PMC article.
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.
Yew MJ, Heywood SE, Ng J, West OM, Pal M, Kueh A, Lancaster GI, Myers S, Yang C, Liu Y, Reibe S, Mellett NA, Meikle PJ, Febbraio MA, Greening DW, Drew BG, Henstridge DC. Yew MJ, et al. Among authors: mellett na. Diabetes Obes Metab. 2024 May;26(5):1731-1745. doi: 10.1111/dom.15484. Epub 2024 Feb 13. Diabetes Obes Metab. 2024. PMID: 38351663
Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts.
Beyene HB, Giles C, Huynh K, Wang T, Cinel M, Mellett NA, Olshansky G, Meikle TG, Watts GF, Hung J, Hui J, Cadby G, Beilby J, Blangero J, Moses EK, Shaw JE, Magliano DJ, Meikle PJ. Beyene HB, et al. Among authors: mellett na. Nat Commun. 2023 Oct 7;14(1):6280. doi: 10.1038/s41467-023-41963-7. Nat Commun. 2023. PMID: 37805498 Free PMC article.
Defining the lipid profiles of human milk, infant formula, and animal milk: implications for infant feeding.
George AD, Paul S, Wang T, Huynh K, Giles C, Mellett N, Duong T, Nguyen A, Geddes D, Mansell T, Saffery R, Vuillermin P, Ponsonby AL, Burgner D, Burugupalli S, Meikle PJ; Barwon Infant Study Investigator Team. George AD, et al. Among authors: mellett n. Front Nutr. 2023 Aug 30;10:1227340. doi: 10.3389/fnut.2023.1227340. eCollection 2023. Front Nutr. 2023. PMID: 37712002 Free PMC article.
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.
Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan CL, McLennan E, Terry LV, Nobis M, Mu A, Nowell C, Horadagoda N, Henstridge DC, Mellett NA, Timpson P, Jones M, Denisenko E, Forrest ARR, Tirnitz-Parker JEE, Meikle PJ, Rose-John S, Karin M, Febbraio MA. Boslem E, et al. Among authors: mellett na. Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703359 Free PMC article.
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis.
Dragoljevic D, Lee MKS, Pernes G, Morgan PK, Louis C, Shihata W, Huynh K, Kochetkova AA, Bell PW, Mellett NA, Meikle PJ, Lancaster GI, Kraakman MJ, Nagareddy PR, Hanaoka BY, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: mellett na. Clin Transl Immunology. 2023 Apr 18;12(4):e1446. doi: 10.1002/cti2.1446. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37091327 Free PMC article.
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJ, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR. Barrachina MN, et al. Among authors: mellett na. bioRxiv [Preprint]. 2023 Feb 12:2023.02.12.527706. doi: 10.1101/2023.02.12.527706. bioRxiv. 2023. PMID: 36798332 Free PMC article. Updated. Preprint.
71 results