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Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids.
Zimmermann C, Watson GM, Bauersfeld L, Berry R, Ciblis B, Lan H, Gerke C, Oberhardt V, Fuchs J, Hofmann M, Freund C, Rossjohn J, Momburg F, Hengel H, Halenius A. Zimmermann C, et al. Among authors: freund c. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2315985121. doi: 10.1073/pnas.2315985121. Epub 2024 Feb 20. Proc Natl Acad Sci U S A. 2024. PMID: 38377192
Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Günther S, Schlundt A, Sticht J, Roske Y, Heinemann U, Wiesmüller KH, Jung G, Falk K, Rötzschke O, Freund C. Günther S, et al. Among authors: freund c. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22219-24. doi: 10.1073/pnas.1014708107. Epub 2010 Nov 29. Proc Natl Acad Sci U S A. 2010. PMID: 21115828 Free PMC article.
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma.
Bräunlein E, Lupoli G, Füchsl F, Abualrous ET, de Andrade Krätzig N, Gosmann D, Wietbrock L, Lange S, Engleitner T, Lan H, Audehm S, Effenberger M, Boxberg M, Steiger K, Chang Y, Yu K, Atay C, Bassermann F, Weichert W, Busch DH, Rad R, Freund C, Antes I, Krackhardt AM. Bräunlein E, et al. Among authors: freund c. J Immunother Cancer. 2021 Sep;9(9):e002754. doi: 10.1136/jitc-2021-002754. J Immunother Cancer. 2021. PMID: 34518289 Free PMC article.
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous ET, Stolzenberg S, Sticht J, Wieczorek M, Roske Y, Günther M, Dähn S, Boesen BB, Calvo MM, Biese C, Kuppler F, Medina-García Á, Álvaro-Benito M, Höfer T, Noé F, Freund C. Abualrous ET, et al. Among authors: freund c. Nat Chem Biol. 2023 Oct;19(10):1196-1204. doi: 10.1038/s41589-023-01316-3. Epub 2023 May 4. Nat Chem Biol. 2023. PMID: 37142807 Free PMC article.
271 results