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Potentiating the radiation-induced type I interferon antitumoral immune response by ATM inhibition in pancreatic cancer.
Zhang Q, Jiang L, Wang W, Huber AK, Valvo VM, Jungles KM, Holcomb EA, Pearson AN, The S, Wang Z, Parsels LA, Parsels JD, Wahl DR, Rao A, Sahai V, Lawrence TS, Green MD, Morgan MA. Zhang Q, et al. Among authors: parsels la. JCI Insight. 2024 Feb 20;9(6):e168824. doi: 10.1172/jci.insight.168824. JCI Insight. 2024. PMID: 38376927 Free PMC article.
Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776.
Engelke CG, Parsels LA, Qian Y, Zhang Q, Karnak D, Robertson JR, Tanska DM, Wei D, Davis MA, Parsels JD, Zhao L, Greenson JK, Lawrence TS, Maybaum J, Morgan MA. Engelke CG, et al. Among authors: parsels jd, parsels la. Clin Cancer Res. 2013 Aug 15;19(16):4412-21. doi: 10.1158/1078-0432.CCR-12-3748. Epub 2013 Jun 26. Clin Cancer Res. 2013. PMID: 23804422 Free PMC article.
Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.
Zhang Q, Green MD, Lang X, Lazarus J, Parsels JD, Wei S, Parsels LA, Shi J, Ramnath N, Wahl DR, Pasca di Magliano M, Frankel TL, Kryczek I, Lei YL, Lawrence TS, Zou W, Morgan MA. Zhang Q, et al. Among authors: parsels la. Cancer Res. 2019 Aug 1;79(15):3940-3951. doi: 10.1158/0008-5472.CAN-19-0761. Epub 2019 May 17. Cancer Res. 2019. PMID: 31101760 Free PMC article.
Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer.
Cuneo KC, Morgan MA, Sahai V, Schipper MJ, Parsels LA, Parsels JD, Devasia T, Al-Hawaray M, Cho CS, Nathan H, Maybaum J, Zalupski MM, Lawrence TS. Cuneo KC, et al. Among authors: parsels la. J Clin Oncol. 2019 Oct 10;37(29):2643-2650. doi: 10.1200/JCO.19.00730. Epub 2019 Aug 9. J Clin Oncol. 2019. PMID: 31398082 Free PMC article. Clinical Trial.
37 results