de Candia M - Search Results

1

Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.

Mugnaini C, Brizzi A, Paolino M, Scarselli E, Castelli R, de Candia M, Gambacorta N, Nicolotti O, Kostrzewa M, Kumar P, Mahmoud AM, Borgonetti V, Iannotta M, Morace A, Galeotti N, Maione S, Altomare CD, Ligresti A, Corelli F. Mugnaini C, et al. Among authors: de candia m. ACS Chem Neurosci. 2024 Mar 6;15(5):955-971. doi: 10.1021/acschemneuro.3c00656. Epub 2024 Feb 19. ACS Chem Neurosci. 2024. PMID: 38372253

2

Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors.

Carotti A, de Candia M, Catto M, Borisova TN, Varlamov AV, Méndez-Alvarez E, Soto-Otero R, Voskressensky LG, Altomare C. Carotti A, et al. Among authors: de candia m. Bioorg Med Chem. 2006 Nov 1;14(21):7205-12. doi: 10.1016/j.bmc.2006.06.055. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843666

3

Fluorinated benzyloxyphenyl piperidine-4-carboxamides with dual function against thrombosis: inhibitors of factor Xa and platelet aggregation.

de Candia M, Liantonio F, Carotti A, De Cristofaro R, Altomare C. de Candia M, et al. Among authors: de cristofaro r. J Med Chem. 2009 Feb 26;52(4):1018-28. doi: 10.1021/jm801141f. J Med Chem. 2009. PMID: 19193009

4

Novel factor Xa inhibitors: a patent review.

de Candia M, Lopopolo G, Altomare C. de Candia M, et al. Expert Opin Ther Pat. 2009 Nov;19(11):1535-80. doi: 10.1517/13543770903270532. Expert Opin Ther Pat. 2009. PMID: 19743898 Review.

5

Biarylmethoxy isonipecotanilides as potent and selective inhibitors of blood coagulation factor Xa.

Lopopolo G, Fiorella F, de Candia M, Nicolotti O, Martel S, Carrupt PA, Altomare C. Lopopolo G, et al. Among authors: de candia m. Eur J Pharm Sci. 2011 Feb 14;42(3):180-91. doi: 10.1016/j.ejps.2010.11.010. Epub 2010 Nov 26. Eur J Pharm Sci. 2011. PMID: 21112391

6

β-D-glucosyl conjugates of highly potent inhibitors of blood coagulation factor Xa bearing 2-chorothiophene as a P1 motif.

Lopopolo G, de Candia M, Panza L, Romano MR, Lograno MD, Campagna F, Altomare C. Lopopolo G, et al. Among authors: de candia m. ChemMedChem. 2012 Sep;7(9):1669-77. doi: 10.1002/cmdc.201200224. Epub 2012 Jul 31. ChemMedChem. 2012. PMID: 22851501

7

Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity.

de Candia M, Fiorella F, Lopopolo G, Carotti A, Romano MR, Lograno MD, Martel S, Carrupt PA, Belviso BD, Caliandro R, Altomare C. de Candia M, et al. J Med Chem. 2013 Nov 14;56(21):8696-711. doi: 10.1021/jm401169a. Epub 2013 Oct 22. J Med Chem. 2013. PMID: 24102612

8

How a β-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties.

Belviso BD, Caliandro R, de Candia M, Zaetta G, Lopopolo G, Incampo F, Colucci M, Altomare CD. Belviso BD, et al. Among authors: de candia m. J Med Chem. 2014 Oct 23;57(20):8563-75. doi: 10.1021/jm5010754. Epub 2014 Oct 14. J Med Chem. 2014. PMID: 25268757

9

New organic nitrate-containing benzyloxy isonipecotanilide derivatives with vasodilatory and anti-platelet activity.

de Candia M, Marini E, Zaetta G, Cellamare S, Di Stilo A, Altomare CD. de Candia M, et al. Eur J Pharm Sci. 2015 May 25;72:69-80. doi: 10.1016/j.ejps.2015.03.004. Epub 2015 Mar 10. Eur J Pharm Sci. 2015. PMID: 25769522 Free article.

10

Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways.

Leo V, Stefanachi A, Nacci C, Leonetti F, de Candia M, Carotti A, Altomare CD, Montagnani M, Cellamare S. Leo V, et al. Among authors: de candia m. J Pharm Pharmacol. 2015 Oct;67(10):1380-92. doi: 10.1111/jphp.12438. Epub 2015 Jun 16. J Pharm Pharmacol. 2015. PMID: 26078032

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