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Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
Mugnaini C, Brizzi A, Paolino M, Scarselli E, Castelli R, de Candia M, Gambacorta N, Nicolotti O, Kostrzewa M, Kumar P, Mahmoud AM, Borgonetti V, Iannotta M, Morace A, Galeotti N, Maione S, Altomare CD, Ligresti A, Corelli F. Mugnaini C, et al. Among authors: castelli r. ACS Chem Neurosci. 2024 Mar 6;15(5):955-971. doi: 10.1021/acschemneuro.3c00656. Epub 2024 Feb 19. ACS Chem Neurosci. 2024. PMID: 38372253
Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD.
Grandi A, Zini I, Palese S, Giorgio C, Tognolini M, Marchesani F, Bruno S, Flammini L, Cantoni AM, Castelli R, Lodola A, Fusari A, Barocelli E, Bertoni S. Grandi A, et al. Among authors: castelli r. Front Pharmacol. 2019 Jun 17;10:691. doi: 10.3389/fphar.2019.00691. eCollection 2019. Front Pharmacol. 2019. PMID: 31297055 Free PMC article.
UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice.
Festuccia C, Gravina GL, Giorgio C, Mancini A, Pellegrini C, Colapietro A, Delle Monache S, Maturo MG, Sferra R, Chiodelli P, Rusnati M, Cantoni A, Castelli R, Vacondio F, Lodola A, Tognolini M. Festuccia C, et al. Among authors: castelli r. Oncotarget. 2018 May 11;9(36):24347-24363. doi: 10.18632/oncotarget.25272. eCollection 2018 May 11. Oncotarget. 2018. PMID: 29849945 Free PMC article.
177 results