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Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
Mugnaini C, Brizzi A, Paolino M, Scarselli E, Castelli R, de Candia M, Gambacorta N, Nicolotti O, Kostrzewa M, Kumar P, Mahmoud AM, Borgonetti V, Iannotta M, Morace A, Galeotti N, Maione S, Altomare CD, Ligresti A, Corelli F. Mugnaini C, et al. Among authors: altomare cd. ACS Chem Neurosci. 2024 Mar 6;15(5):955-971. doi: 10.1021/acschemneuro.3c00656. Epub 2024 Feb 19. ACS Chem Neurosci. 2024. PMID: 38372253
Radiosynthesis and whole-body distribution in mice of a 18 F-labeled azepino[4,3-b]indole-1-one derivative with multimodal activity for the treatment of Alzheimer's disease.
Lee SH, Purgatorio R, Samarelli F, Catto M, Denora N, Morgese MG, Tucci P, Trabace L, Kim HW, Park HS, Kim SE, Lee BC, de Candia M, Altomare CD. Lee SH, et al. Among authors: altomare cd. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300491. doi: 10.1002/ardp.202300491. Epub 2023 Dec 29. Arch Pharm (Weinheim). 2024. PMID: 38158335
Short-term anti-remodeling effects of gliflozins in diabetic patients with heart failure and reduced ejection fraction: an explainable artificial intelligence approach.
Mele M, Imbrici P, Mele A, Togo MV, Dinoi G, Correale M, Brunetti ND, Nicolotti O, De Luca A, Altomare CD, Liantonio A, Amoroso N. Mele M, et al. Among authors: altomare cd. Front Pharmacol. 2023 Jun 9;14:1175606. doi: 10.3389/fphar.2023.1175606. eCollection 2023. Front Pharmacol. 2023. PMID: 37361206 Free PMC article.
Making sense of chemical space network shows signs of criticality.
Amoroso N, Gambacorta N, Mastrolorito F, Togo MV, Trisciuzzi D, Monaco A, Pantaleo E, Altomare CD, Ciriaco F, Nicolotti O. Amoroso N, et al. Among authors: altomare cd. Sci Rep. 2023 Dec 4;13(1):21335. doi: 10.1038/s41598-023-48107-3. Sci Rep. 2023. PMID: 38049451 Free PMC article.
Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance.
Nevskaya AA, Purgatorio R, Borisova TN, Varlamov AV, Anikina LV, Obydennik AY, Nevskaya EY, Niso M, Colabufo NA, Carrieri A, Catto M, de Candia M, Voskressensky LG, Altomare CD. Nevskaya AA, et al. Among authors: altomare cd. Pharmaceuticals (Basel). 2024 Apr 22;17(4):539. doi: 10.3390/ph17040539. Pharmaceuticals (Basel). 2024. PMID: 38675499 Free PMC article.
73 results