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The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.
Dias da Silva D, Ferreira B, Roque Bravo R, Rebelo R, Duarte de Almeida T, Valente MJ, Silva JP, Carvalho F, Bastos ML, Carmo H. Dias da Silva D, et al. Among authors: carvalho f. Arch Toxicol. 2019 Sep;93(9):2617-2634. doi: 10.1007/s00204-019-02539-x. Epub 2019 Aug 29. Arch Toxicol. 2019. PMID: 31468101
Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis.
Andronis C, Silva JP, Lekka E, Virvilis V, Carmo H, Bampali K, Ernst M, Hu Y, Loryan I, Richard J, Carvalho F, Savić MM. Andronis C, et al. Among authors: carvalho f. Arch Toxicol. 2020 Aug;94(8):2829-2845. doi: 10.1007/s00204-020-02788-1. Epub 2020 Jun 5. Arch Toxicol. 2020. PMID: 32504122 Free PMC article.
In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV).
Araújo AM, Carvalho M, Costa VM, Duarte JA, Dinis-Oliveira RJ, Bastos ML, Guedes de Pinho P, Carvalho F. Araújo AM, et al. Among authors: carvalho m, carvalho f. Arch Toxicol. 2021 Feb;95(2):509-527. doi: 10.1007/s00204-020-02949-2. Epub 2020 Nov 19. Arch Toxicol. 2021. PMID: 33215236
2,584 results