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Early antiretroviral therapy and its impact on natural killer cell dynamics in HIV-1 infected men who have sex with men: a cross-sectional pilot study evaluating the impact of early ART initiation on NK cell perturbation in HIV infection.
Akiso M, Muema D, Langat R, Naidoo KK, Oino G, Mutua G, Thobakgale C, Ochiel D, Chinyenze K, Anzala O, Mureithi MW. Akiso M, et al. Among authors: thobakgale c. Microbiol Spectr. 2024 Apr 2;12(4):e0357023. doi: 10.1128/spectrum.03570-23. Epub 2024 Feb 16. Microbiol Spectr. 2024. PMID: 38364104 Free PMC article.
Reduced Expression of Siglec-7, NKG2A, and CD57 on Terminally Differentiated CD56-CD16+ Natural Killer Cell Subset Is Associated with Natural Killer Cell Dysfunction in Chronic HIV-1 Clade C Infection.
Zulu MZ, Naidoo KK, Mncube Z, Jaggernath M, Goulder PJR, Ndung'u T, Altfeld M, Thobakgale CF. Zulu MZ, et al. Among authors: thobakgale cf. AIDS Res Hum Retroviruses. 2017 Dec;33(12):1205-1213. doi: 10.1089/AID.2017.0095. Epub 2017 Sep 21. AIDS Res Hum Retroviruses. 2017. PMID: 28810810
Low Immune Activation in Early Pregnancy Is Associated With Preterm But Not Small-for-gestational-age Delivery in Women Infected With Human Immunodeficiency Virus Initiating Antiretroviral Therapy in Pregnancy: A Prematurity Immunology in HIV-infected Mothers and their Infants Study (PIMS) Case-control Study in Cape Town, South Africa.
Mdletshe N, Thobakgale C, Malaba TR, Madlala H, Myer L, Muema DM, Mogeni P, Gray CM, Altfeld M, Newell ML, Ndung'u T. Mdletshe N, et al. Among authors: thobakgale c. Clin Infect Dis. 2021 Dec 16;73(12):2205-2216. doi: 10.1093/cid/ciab151. Clin Infect Dis. 2021. PMID: 33606024 Free PMC article.
HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.
Ziegler MC, Naidoo K, Chapel A, Nkotwana S, Mann J, Mncube Z, Ismael N, Goulder P, Ndung'u T, Altfeld M, Thobakgale CF. Ziegler MC, et al. Among authors: thobakgale cf. AIDS. 2021 Jan 1;35(1):151-154. doi: 10.1097/QAD.0000000000002721. AIDS. 2021. PMID: 33273184 Free PMC article.
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype.
Vieira V, Lim N, Singh A, Leitman E, Dsouza R, Adland E, Muenchhoff M, Roider J, Marin Lopez M, Carabelli J, Giandhari J, Groll A, Jooste P, Prado JG, Thobakgale C, Dong K, Kiepiela P, Prendergast AJ, Tudor-Williams G, Frater J, Walker BD, Ndung'u T, Ramsuran V, Leslie A, Kløverpris HN, Goulder P. Vieira V, et al. Among authors: thobakgale c. JCI Insight. 2023 Feb 8;8(3):e156049. doi: 10.1172/jci.insight.156049. JCI Insight. 2023. PMID: 36602861 Free PMC article.
Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants.
Ramduth D, Thobakgale CF, Mkhwanazi NP, De Pierres C, Reddy S, van der Stok M, Mncube Z, Mphatswe W, Blanckenberg N, Cengimbo A, Prendergast A, Tudor-Williams G, Dong K, Jeena P, Coovadia HM, Day CL, Kiepiela P, Goulder PJ, Walker BD. Ramduth D, et al. Among authors: thobakgale cf. AIDS Res Hum Retroviruses. 2008 Feb;24(2):265-70. doi: 10.1089/aid.2007.0096. AIDS Res Hum Retroviruses. 2008. PMID: 18284325
34 results