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β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.
Zhang Y, Xu H, Cui G, Liang B, Chen X, Ko S, Affo S, Song X, Liao Y, Feng J, Wang P, Wang H, Xu M, Wang J, Pes GM, Ribback S, Zeng Y, Singhi A, Schwabe RF, Monga SP, Evert M, Tang L, Calvisi DF, Chen X. Zhang Y, et al. Among authors: chen x. Gastroenterology. 2022 Aug;163(2):481-494. doi: 10.1053/j.gastro.2022.04.028. Epub 2022 Apr 27. Gastroenterology. 2022. PMID: 35489428 Free PMC article.
RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues.
Scheiter A, Evert K, Reibenspies L, Cigliano A, Annweiler K, Müller K, Pöhmerer LM, Xu H, Cui G, Itzel T, Materna-Reichelt S, Coluccio A, Honarnejad K, Teufel A, Brochhausen C, Dombrowski F, Chen X, Evert M, Calvisi DF, Utpatel K. Scheiter A, et al. Among authors: chen x. Mol Oncol. 2022 Mar;16(5):1091-1118. doi: 10.1002/1878-0261.13135. Epub 2021 Nov 20. Mol Oncol. 2022. PMID: 34748271 Free PMC article.
FATP5 Is Indispensable for the Growth of Intrahepatic Cholangiocarcinoma.
Shihadih D, Wang X, Zushin PH, Khodakivskyi P, Park HM, Tso E, Shiblak J, Misic A, Louie SM, Ward C, Hellerstein M, Nomura DK, Goun E, Urigo F, Calvisi DF, Chen X, Stahl A. Shihadih D, et al. Among authors: chen x. Mol Cancer Res. 2024 Jun 4;22(6):585-595. doi: 10.1158/1541-7786.MCR-23-0389. Mol Cancer Res. 2024. PMID: 38358323
SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial-Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model.
Xu M, Wang J, Xu Z, Li R, Wang P, Shang R, Cigliano A, Ribback S, Solinas A, Pes GM, Evert K, Wang H, Song X, Zhang S, Che L, Pascale RM, Calvisi DF, Liu Q, Chen X. Xu M, et al. Among authors: chen x. Cancer Res. 2019 Nov 1;79(21):5563-5574. doi: 10.1158/0008-5472.CAN-18-3750. Epub 2019 Aug 5. Cancer Res. 2019. PMID: 31383647 Free PMC article.
β-Catenin signaling in hepatocellular carcinoma.
Xu C, Xu Z, Zhang Y, Evert M, Calvisi DF, Chen X. Xu C, et al. Among authors: chen x. J Clin Invest. 2022 Feb 15;132(4):e154515. doi: 10.1172/JCI154515. J Clin Invest. 2022. PMID: 35166233 Free PMC article. Review.
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Cigliano A, Zhang S, Ribback S, Steinmann S, Sini M, Ament CE, Utpatel K, Song X, Wang J, Pilo MG, Berger F, Wang H, Tao J, Li X, Pes GM, Mancarella S, Giannelli G, Dombrowski F, Evert M, Calvisi DF, Chen X, Evert K. Cigliano A, et al. Among authors: chen x. J Exp Clin Cancer Res. 2022 Jun 3;41(1):192. doi: 10.1186/s13046-022-02394-2. J Exp Clin Cancer Res. 2022. PMID: 35655220 Free PMC article.
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