Wiseman RL - Search Results

1

Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations.

Madrazo N, Khattar Z, Powers ET, Rosarda JD, Wiseman RL. Madrazo N, et al. Among authors: wiseman rl. bioRxiv [Preprint]. 2024 Feb 1:2024.01.30.577830. doi: 10.1101/2024.01.30.577830. bioRxiv. 2024. PMID: 38352575 Free PMC article. Updated. Preprint.

2

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

Hammarström P, Wiseman RL, Powers ET, Kelly JW. Hammarström P, et al. Among authors: wiseman rl. Science. 2003 Jan 31;299(5607):713-6. doi: 10.1126/science.1079589. Science. 2003. PMID: 12560553

3

Partitioning conformational intermediates between competing refolding and aggregation pathways: insights into transthyretin amyloid disease.

Wiseman RL, Powers ET, Kelly JW. Wiseman RL, et al. Biochemistry. 2005 Dec 20;44(50):16612-23. doi: 10.1021/bi0511484. Biochemistry. 2005. PMID: 16342952 Free PMC article.

4

An adaptable standard for protein export from the endoplasmic reticulum.

Wiseman RL, Powers ET, Buxbaum JN, Kelly JW, Balch WE. Wiseman RL, et al. Cell. 2007 Nov 16;131(4):809-21. doi: 10.1016/j.cell.2007.10.025. Cell. 2007. PMID: 18022373 Free article.

5

Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1.

Ryno LM, Genereux JC, Naito T, Morimoto RI, Powers ET, Shoulders MD, Wiseman RL. Ryno LM, et al. Among authors: wiseman rl. ACS Chem Biol. 2014 Jun 20;9(6):1273-83. doi: 10.1021/cb500062n. Epub 2014 Apr 16. ACS Chem Biol. 2014. PMID: 24689980 Free PMC article.

6

Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity.

Murray AN, Chen W, Antonopoulos A, Hanson SR, Wiseman RL, Dell A, Haslam SM, Powers DL, Powers ET, Kelly JW. Murray AN, et al. Among authors: wiseman rl. Chem Biol. 2015 Aug 20;22(8):1052-62. doi: 10.1016/j.chembiol.2015.06.017. Epub 2015 Jul 16. Chem Biol. 2015. PMID: 26190824 Free PMC article.

7

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.

Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW. Plate L, et al. Among authors: wiseman rl. Elife. 2016 Jul 20;5:e15550. doi: 10.7554/eLife.15550. Elife. 2016. PMID: 27435961 Free PMC article.

8

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress.

Lebeau J, Saunders JM, Moraes VWR, Madhavan A, Madrazo N, Anthony MC, Wiseman RL. Lebeau J, et al. Among authors: wiseman rl. Cell Rep. 2018 Mar 13;22(11):2827-2836. doi: 10.1016/j.celrep.2018.02.055. Cell Rep. 2018. PMID: 29539413 Free PMC article.

9

A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.

Giadone RM, Rosarda JD, Akepati PR, Thomas AC, Boldbaatar B, James MF, Wilson AA, Sanchorawala V, Connors LH, Berk JL, Wiseman RL, Murphy GJ. Giadone RM, et al. Among authors: wiseman rl. Amyloid. 2018 Sep;25(3):148-155. doi: 10.1080/13506129.2018.1489228. Epub 2018 Jul 21. Amyloid. 2018. PMID: 30032658 Free PMC article.

10

Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.

Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW. Paxman R, et al. Among authors: wiseman rl. Elife. 2018 Aug 7;7:e37168. doi: 10.7554/eLife.37168. Elife. 2018. PMID: 30084354 Free PMC article.

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