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Page 1
Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer.
Poluben L, Nouri M, Liang J, Varkaris A, Ersoy-Fazlioglu B, Voznesensky O, Lee II, Qiu X, Cato L, Seo JH, Freedman ML, Sowalsky AG, Lack NA, Corey E, Nelson PS, Brown M, Long HW, Balk SP, Russo JW. Poluben L, et al. Among authors: lack na. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575110. doi: 10.1101/2024.01.10.575110. bioRxiv. 2024. PMID: 38260576 Free PMC article. Preprint.
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.
Joosten SEP, Gregoricchio S, Stelloo S, Yapıcı E, Huang CF, Yavuz K, Donaldson Collier M, Morova T, Altintaş UB, Kim Y, Canisius S, Moelans CB, van Diest PJ, Korkmaz G, Lack NA, Vermeulen M, Linn SC, Zwart W. Joosten SEP, et al. Among authors: lack na. Genome Res. 2024 May 15;34(4):539-555. doi: 10.1101/gr.278680.123. Genome Res. 2024. PMID: 38719469
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
Ozyerli-Goknar E, Kala EY, Aksu AC, Bulut I, Cingöz A, Nizamuddin S, Biniossek M, Seker-Polat F, Morova T, Aztekin C, Kung SHY, Syed H, Tuncbag N, Gönen M, Philpott M, Cribbs AP, Acilan C, Lack NA, Onder TT, Timmers HTM, Bagci-Onder T. Ozyerli-Goknar E, et al. Among authors: lack na. Cell Commun Signal. 2023 Nov 16;21(1):328. doi: 10.1186/s12964-023-01335-6. Cell Commun Signal. 2023. PMID: 37974198 Free PMC article.
Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output.
Joosten SE, Gregoricchio S, Stelloo S, Yapıcı E, Huang CF, Collier MD, Morova T, Altintas B, Kim Y, Canisius S, Korkmaz G, Lack N, Vermeulen M, Linn SC, Zwart W. Joosten SE, et al. Among authors: lack n. bioRxiv [Preprint]. 2023 Nov 2:2023.10.30.564691. doi: 10.1101/2023.10.30.564691. bioRxiv. 2023. PMID: 37961147 Free PMC article. Preprint.
129 results