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Human Trophoblast Stem Cells Restrict Human Cytomegalovirus Replication.
Rollman TB, Berkebile ZW, Okae H, Bardwell VJ, Gearhart MD, Bierle CJ. Rollman TB, et al. Among authors: bardwell vj. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571456. doi: 10.1101/2023.12.13.571456. bioRxiv. 2023. PMID: 38168202 Free PMC article. Updated. Preprint.
Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration.
Langouët M, Jolicoeur C, Javed A, Mattar P, Gearhart MD, Daiger SP, Bertelsen M, Tranebjærg L, Rendtorff ND, Grønskov K, Jespersgaard C, Chen R, Sun Z, Li H, Alirezaie N, Majewski J, Bardwell VJ, Sui R, Koenekoop RK, Cayouette M. Langouët M, et al. Among authors: bardwell vj. Sci Adv. 2022 Sep 9;8(36):eabh2868. doi: 10.1126/sciadv.abh2868. Epub 2022 Sep 7. Sci Adv. 2022. PMID: 36070393 Free PMC article.
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.
Schaefer EJ, Wang HC, Karp HQ, Meyer CA, Cejas P, Gearhart MD, Adelman ER, Fares I, Apffel A, Lim K, Xie Y, Gibson CJ, Schenone M, Murdock HM, Wang ES, Gondek LP, Carroll MP, Vedula RS, Winer ES, Garcia JS, Stone RM, Luskin MR, Carr SA, Long HW, Bardwell VJ, Figueroa ME, Lindsley RC. Schaefer EJ, et al. Among authors: bardwell vj. Blood Cancer Discov. 2022 Mar 1;3(2):116-135. doi: 10.1158/2643-3230.BCD-21-0115. Blood Cancer Discov. 2022. PMID: 35015684 Free PMC article.
Loss of function mutations of BCOR in classical Hodgkin lymphoma.
Giefing M, Gearhart MD, Schneider M, Overbeck B, Klapper W, Hartmann S, Ustaszewski A, Weniger MA, Wiehle L, Hansmann ML, Melnick A, Béguelin W, Sundström C, Küppers R, Bardwell VJ, Siebert R. Giefing M, et al. Among authors: bardwell vj. Leuk Lymphoma. 2022 May;63(5):1080-1090. doi: 10.1080/10428194.2021.2015587. Epub 2021 Dec 27. Leuk Lymphoma. 2022. PMID: 34957890
Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Kutscher LM, Okonechnikov K, Batora NV, Clark J, Silva PBG, Vouri M, van Rijn S, Sieber L, Statz B, Gearhart MD, Shiraishi R, Mack N, Orr BA, Korshunov A, Gudenas BL, Smith KS, Mercier AL, Ayrault O, Hoshino M, Kool M, von Hoff K, Graf N, Fleischhack G, Bardwell VJ, Pfister SM, Northcott PA, Kawauchi D. Kutscher LM, et al. Among authors: bardwell vj. Genes Dev. 2020 Sep 1;34(17-18):1161-1176. doi: 10.1101/gad.337584.120. Epub 2020 Aug 20. Genes Dev. 2020. PMID: 32820036 Free PMC article.
62 results