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Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences.
Rekima A, van den Elsen L, Isnard C, Smyth DJ, Lynn MA, Yee T, Stevens NE, Machado S, Divakara N, Bhasin M, Tjiam MC, Rowel C, Servant F, Burcelin R, Locksley R, Maizels R, Lynn DJ, Egwang T, Verhasselt V. Rekima A, et al. Among authors: locksley r. Allergy. 2024 Feb 13. doi: 10.1111/all.16054. Online ahead of print. Allergy. 2024. PMID: 38348877 No abstract available.
Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains.
Zwick RK, Kasparek P, Palikuqi B, Viragova S, Weichselbaum L, McGinnis CS, McKinley KL, Rathnayake A, Vaka D, Nguyen V, Trentesaux C, Reyes E, Gupta AR, Gartner ZJ, Locksley RM, Gardner JM, Itzkovitz S, Boffelli D, Klein OD. Zwick RK, et al. Among authors: locksley rm. Nat Cell Biol. 2024 Feb;26(2):250-262. doi: 10.1038/s41556-023-01337-z. Epub 2024 Feb 6. Nat Cell Biol. 2024. PMID: 38321203
Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains.
Zwick RK, Kasparek P, Palikuqi B, Viragova S, Weichselbaum L, McGinnis CS, McKinley KL, Rathnayake A, Vaka D, Nguyen V, Trentesaux C, Reyes E, Gupta AR, Gartner ZJ, Locksley RM, Gardner JM, Itzkovitz S, Boffelli D, Klein OD. Zwick RK, et al. Among authors: locksley rm. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558726. doi: 10.1101/2023.09.20.558726. bioRxiv. 2023. PMID: 37790430 Free PMC article. Updated. Preprint.
Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites.
Shaikh N, Waterhölter A, Gnirck AC, Becker M, Adamiak V, Henneken L, Wunderlich M, Hartmann W, Linnemann L, Huber TB, Krebs CF, Panzer U, Locksley RM, Wilhelm C, Breloer M, Turner JE. Shaikh N, et al. Among authors: locksley rm. J Exp Med. 2023 Dec 4;220(12):e20221015. doi: 10.1084/jem.20221015. Epub 2023 Sep 29. J Exp Med. 2023. PMID: 37773047 Free PMC article.
Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis.
Sbierski-Kind J, Cautivo KM, Wagner JC, Dahlgren MW, Nilsson J, Krasilnikov M, Mroz NM, Lizama CO, Gan AL, Matatia PR, Taruselli MT, Chang AA, Caryotakis S, O'Leary CE, Kotas M, Mattis AN, Peng T, Locksley RM, Molofsky AB. Sbierski-Kind J, et al. Among authors: locksley rm. bioRxiv [Preprint]. 2023 Apr 28:2023.04.26.537913. doi: 10.1101/2023.04.26.537913. bioRxiv. 2023. PMID: 37163060 Free PMC article. Preprint.
The ins and outs of innate and adaptive type 2 immunity.
Molofsky AB, Locksley RM. Molofsky AB, et al. Among authors: locksley rm. Immunity. 2023 Apr 11;56(4):704-722. doi: 10.1016/j.immuni.2023.03.014. Immunity. 2023. PMID: 37044061 Free PMC article. Review.
277 results