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Geometric parameters that affect the behavior of logic-gated CAR T cells.
Partin AC, Bruno R, Shafaattalab S, Vander Mause E, Winters A, Daris M, Gahrs C, Jette CA, DiAndreth B, Sandberg ML, Hamburger AE, Kamb A, Riley TP. Partin AC, et al. Among authors: riley tp. Front Immunol. 2024 Jan 26;15:1304765. doi: 10.3389/fimmu.2024.1304765. eCollection 2024. Front Immunol. 2024. PMID: 38343543 Free PMC article.
HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Mock JY, Winters A, Riley TP, Bruno R, Naradikian MS, Sharma S, Jette CA, Elshimali R, Gahrs C, Toledo-Warshaviak D, West AP Jr, Kamb A, Hamburger AE. Mock JY, et al. Among authors: riley tp. Mol Ther Oncolytics. 2022 Oct 4;27:157-166. doi: 10.1016/j.omto.2022.09.010. eCollection 2022 Dec 15. Mol Ther Oncolytics. 2022. PMID: 36381658 Free PMC article.
Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features.
Harmalkar A, Rao R, Richard Xie Y, Honer J, Deisting W, Anlahr J, Hoenig A, Czwikla J, Sienz-Widmann E, Rau D, Rice AJ, Riley TP, Li D, Catterall HB, Tinberg CE, Gray JJ, Wei KY. Harmalkar A, et al. Among authors: riley tp. MAbs. 2023 Jan-Dec;15(1):2163584. doi: 10.1080/19420862.2022.2163584. MAbs. 2023. PMID: 36683173 Free PMC article.
Next generation Fc scaffold for multispecific antibodies.
Estes B, Sudom A, Gong D, Whittington DA, Li V, Mohr C, Li D, Riley TP, Shi SD, Zhang J, Garces F, Wang Z. Estes B, et al. Among authors: riley tp. iScience. 2021 Nov 15;24(12):103447. doi: 10.1016/j.isci.2021.103447. eCollection 2021 Dec 17. iScience. 2021. PMID: 34877503 Free PMC article.
Structure Based Prediction of Neoantigen Immunogenicity.
Riley TP, Keller GLJ, Smith AR, Davancaze LM, Arbuiso AG, Devlin JR, Baker BM. Riley TP, et al. Front Immunol. 2019 Aug 28;10:2047. doi: 10.3389/fimmu.2019.02047. eCollection 2019. Front Immunol. 2019. PMID: 31555277 Free PMC article.
Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Hellman LM, Foley KC, Singh NK, Alonso JA, Riley TP, Devlin JR, Ayres CM, Keller GLJ, Zhang Y, Vander Kooi CW, Nishimura MI, Baker BM. Hellman LM, et al. Among authors: riley tp. Mol Ther. 2019 Feb 6;27(2):300-313. doi: 10.1016/j.ymthe.2018.12.010. Epub 2018 Dec 14. Mol Ther. 2019. PMID: 30617019 Free PMC article.
23 results