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Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.
Becker AMD, Decker AH, Flórez-Grau G, Bakdash G, Röring RJ, Stelloo S, Vermeulen M, Piet B, Aarntzen EHJG, Verdoes M, de Vries IJM. Becker AMD, et al. Among authors: florez grau g. Cell Rep Med. 2024 Feb 20;5(2):101386. doi: 10.1016/j.xcrm.2023.101386. Epub 2024 Jan 18. Cell Rep Med. 2024. PMID: 38242119 Free PMC article.
Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways.
van Wigcheren GF, Cuenca-Escalona J, Stelloo S, Brake J, Peeters E, Horrevorts SK, Frölich S, Ramos-Tomillero I, Wesseling-Rozendaal Y, van Herpen CML, van de Stolpe A, Vermeulen M, de Vries IJM, Figdor CG, Flórez-Grau G. van Wigcheren GF, et al. Among authors: florez grau g. J Biol Chem. 2023 Nov;299(11):105276. doi: 10.1016/j.jbc.2023.105276. Epub 2023 Sep 20. J Biol Chem. 2023. PMID: 37739035 Free PMC article.
Guidelines for mouse and human DC generation.
Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M. Lutz MB, et al. Among authors: florez grau g. Eur J Immunol. 2023 Nov;53(11):e2249816. doi: 10.1002/eji.202249816. Epub 2022 Oct 27. Eur J Immunol. 2023. PMID: 36303448 Free PMC article.
Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion.
Le Gall C, Cammarata A, de Haas L, Ramos-Tomillero I, Cuenca-Escalona J, Schouren K, Wijfjes Z, Becker AMD, Bödder J, Dölen Y, de Vries IJM, Figdor CG, Flórez-Grau G, Verdoes M. Le Gall C, et al. Among authors: florez grau g. J Immunother Cancer. 2022 Apr;10(4):e004309. doi: 10.1136/jitc-2021-004309. J Immunother Cancer. 2022. PMID: 35428705 Free PMC article.
Recent Advances and Future Perspective of DC-Based Therapy in NSCLC.
van der Hoorn IAE, Flórez-Grau G, van den Heuvel MM, de Vries IJM, Piet B. van der Hoorn IAE, et al. Among authors: florez grau g. Front Immunol. 2021 Jun 28;12:704776. doi: 10.3389/fimmu.2021.704776. eCollection 2021. Front Immunol. 2021. PMID: 34262573 Free PMC article. Review.
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