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119 results

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Page 1
Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin-angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial.
Gutierrez Del Arroyo A, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S, Brealey D, Pearse RM, Ackland GL; SPACE trial investigators. Gutierrez Del Arroyo A, et al. Among authors: brealey d. Br J Anaesth. 2024 May;132(5):857-866. doi: 10.1016/j.bja.2024.01.010. Epub 2024 Feb 9. Br J Anaesth. 2024. PMID: 38341283 Free PMC article. Clinical Trial.
Discontinuation vs. continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial.
Ackland GL, Patel A, Abbott TEF, Begum S, Dias P, Crane DR, Somanath S, Middleditch A, Cleland S, Gutierrez Del Arroyo A, Brealey D, Pearse RM; Stopping Perioperative ACE-inhibitors or angiotensin-II receptor blockers (SPACE) trial investigators. Ackland GL, et al. Among authors: brealey d. Eur Heart J. 2024 Apr 1;45(13):1146-1155. doi: 10.1093/eurheartj/ehad716. Eur Heart J. 2024. PMID: 37935833 Free PMC article. Clinical Trial.
Critical care utilisation for patients receiving chimeric antigen receptor (CAR) T cell therapy in the UK.
Pirani T, Wilson A, Brealey D, Low R, O'Neill S, Le J, Jhanji S, Bangash MN, Mathew A, Wright C, Latif AL, Irvine D, Kasipandian V, Singh N, Saha R, Metaxa V. Pirani T, et al. Among authors: brealey d. Br J Anaesth. 2024 May;132(5):1004-1006. doi: 10.1016/j.bja.2024.01.047. Epub 2024 Mar 22. Br J Anaesth. 2024. PMID: 38521658 No abstract available.
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P; GenOMICC Investigators; SCOURGE Consortium; ISARICC Investigators; 23andMe COVID-19 Team; Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK. Pairo-Castineira E, et al. Nature. 2023 May;617(7962):764-768. doi: 10.1038/s41586-023-06034-3. Epub 2023 May 17. Nature. 2023. PMID: 37198478 Free PMC article.
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P; GenOMICC Investigators; SCOURGE Consortium; ISARICC Investigators; 23andMe COVID-19 Team; Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK. Pairo-Castineira E, et al. Nature. 2023 Jul;619(7971):E61. doi: 10.1038/s41586-023-06383-z. Nature. 2023. PMID: 37433877 Free PMC article. No abstract available.
Diagnosing sepsis: where we're at and where we're going.
Zimmermann T, Brealey D, Singer M. Zimmermann T, et al. Among authors: brealey d. Intensive Care Med. 2024 May 2. doi: 10.1007/s00134-024-07428-1. Online ahead of print. Intensive Care Med. 2024. PMID: 38695925 No abstract available.
Early dynamic changes to monocytes following major surgery are associated with subsequent infections.
Snow TAC, Waller AV, Loye R, Ryckaert F, Cesar A, Saleem N, Roy R, Whittle J, Al-Hindawi A, Das A, Singer M, Brealey D, Arulkumaran N; University College London Hospitals Critical Care Research Team. Snow TAC, et al. Among authors: brealey d. Front Immunol. 2024 Apr 9;15:1352556. doi: 10.3389/fimmu.2024.1352556. eCollection 2024. Front Immunol. 2024. PMID: 38655251 Free PMC article.
Immunophenotyping patients with sepsis and underlying haematological malignancy reveals defects in monocyte and lymphocyte function.
Snow TAC, Serisier A, Brealey D, Singer M, Arulkumaran N; University College London Hospitals Critical Care Research Team. Snow TAC, et al. Among authors: brealey d. Intensive Care Med Exp. 2024 Jan 11;12(1):3. doi: 10.1186/s40635-023-00578-4. Intensive Care Med Exp. 2024. PMID: 38206543 Free PMC article. No abstract available.
119 results