Haigh TA - Search Results

1

Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological response.

Jackson HK, Long HM, Yam-Puc JC, Palmulli R, Haigh TA, Gerber PP, Lee JS, Matheson NJ, Young L, Trowsdale J, Lo M, Taylor GS, Thaventhiran JE, Edgar JR. Jackson HK, et al. Among authors: haigh ta. J Extracell Vesicles. 2024 Feb;13(2):e12412. doi: 10.1002/jev2.12412. J Extracell Vesicles. 2024. PMID: 38339765 Free PMC article.

2

Mutations in SARS-CoV-2 spike protein impair epitope-specific CD4⁺ T cell recognition.

Tye EXC, Jinks E, Haigh TA, Kaul B, Patel P, Parry HM, Newby ML, Crispin M, Kaur N, Moss P, Drennan SJ, Taylor GS, Long HM. Tye EXC, et al. Among authors: haigh ta. Nat Immunol. 2022 Dec;23(12):1726-1734. doi: 10.1038/s41590-022-01351-7. Epub 2022 Dec 1. Nat Immunol. 2022. PMID: 36456735

3

Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors.

Dowell AC, Haigh TA, Ryan GB, Turner JE, Long HM, Taylor GS. Dowell AC, et al. Among authors: haigh ta. PLoS Pathog. 2021 Dec 9;17(12):e1010137. doi: 10.1371/journal.ppat.1010137. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34882759 Free PMC article.

4

Epstein-Barr virus evades CD4+ T cell responses in lytic cycle through BZLF1-mediated downregulation of CD74 and the cooperation of vBcl-2.

Zuo J, Thomas WA, Haigh TA, Fitzsimmons L, Long HM, Hislop AD, Taylor GS, Rowe M. Zuo J, et al. Among authors: haigh ta. PLoS Pathog. 2011 Dec;7(12):e1002455. doi: 10.1371/journal.ppat.1002455. Epub 2011 Dec 22. PLoS Pathog. 2011. PMID: 22216005 Free PMC article.

5

A role for intercellular antigen transfer in the recognition of EBV-transformed B cell lines by EBV nuclear antigen-specific CD4+ T cells.

Taylor GS, Long HM, Haigh TA, Larsen M, Brooks J, Rickinson AB. Taylor GS, et al. Among authors: haigh ta. J Immunol. 2006 Sep 15;177(6):3746-56. doi: 10.4049/jimmunol.177.6.3746. J Immunol. 2006. PMID: 16951335

6

The role of tetraspanin CD63 in antigen presentation via MHC class II.

Petersen SH, Odintsova E, Haigh TA, Rickinson AB, Taylor GS, Berditchevski F. Petersen SH, et al. Among authors: haigh ta. Eur J Immunol. 2011 Sep;41(9):2556-61. doi: 10.1002/eji.201141438. Epub 2011 Aug 4. Eur J Immunol. 2011. PMID: 21660937 Free article.

7

Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4⁺ T cell immunity.

Chen Y, Mason GH, Scourfield DO, Greenshields-Watson A, Haigh TA, Sewell AK, Long HM, Gallimore AM, Rizkallah P, MacLachlan BJ, Godkin A. Chen Y, et al. Among authors: haigh ta. Cell Rep. 2023 Aug 29;42(8):112827. doi: 10.1016/j.celrep.2023.112827. Epub 2023 Jul 19. Cell Rep. 2023. PMID: 37471227 Free PMC article.

8

Regression of Epstein-Barr virus-induced B-cell transformation in vitro involves virus-specific CD8+ T cells as the principal effectors and a novel CD4+ T-cell reactivity.

Gudgeon NH, Taylor GS, Long HM, Haigh TA, Rickinson AB. Gudgeon NH, et al. Among authors: haigh ta. J Virol. 2005 May;79(9):5477-88. doi: 10.1128/JVI.79.9.5477-5488.2005. J Virol. 2005. PMID: 15827162 Free PMC article.

9

A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy.

Fox CP, Haigh TA, Taylor GS, Long HM, Lee SP, Shannon-Lowe C, O'Connor S, Bollard CM, Iqbal J, Chan WC, Rickinson AB, Bell AI, Rowe M. Fox CP, et al. Among authors: haigh ta. Blood. 2010 Nov 11;116(19):3695-704. doi: 10.1182/blood-2010-06-292268. Epub 2010 Jul 29. Blood. 2010. PMID: 20671118 Free PMC article. Clinical Trial.

10

EBV-specific CD4+ T cell clones exhibit vigorous allogeneic responses.

Landais E, Morice A, Long HM, Haigh TA, Charreau B, Bonneville M, Taylor GS, Houssaint E. Landais E, et al. Among authors: haigh ta. J Immunol. 2006 Aug 1;177(3):1427-33. doi: 10.4049/jimmunol.177.3.1427. J Immunol. 2006. PMID: 16849448

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