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A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization.
Volmert B, Kiselev A, Juhong A, Wang F, Riggs A, Kostina A, O'Hern C, Muniyandi P, Wasserman A, Huang A, Lewis-Israeli Y, Panda V, Bhattacharya S, Lauver A, Park S, Qiu Z, Zhou C, Aguirre A. Volmert B, et al. Among authors: kostina a. Nat Commun. 2023 Dec 12;14(1):8245. doi: 10.1038/s41467-023-43999-1. Nat Commun. 2023. PMID: 38086920 Free PMC article.
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis.
Neuwirt E, Magnani G, Ćiković T, Wöhrle S, Fischer L, Kostina A, Flemming S, Fischenich NJ, Saller BS, Gorka O, Renner S, Agarinis C, Parker CN, Boettcher A, Farady CJ, Kesselring R, Berlin C, Backofen R, Rodriguez-Franco M, Kreutz C, Prinz M, Tholen M, Reinheckel T, Ott T, Groß CJ, Jost PJ, Groß O. Neuwirt E, et al. Among authors: kostina a. Sci Signal. 2023 Jan 17;16(768):eabh1083. doi: 10.1126/scisignal.abh1083. Epub 2023 Jan 17. Sci Signal. 2023. PMID: 36649377
Modeling of Retinal Degeneration.
Suetov AA, Boiko EV, Alekperov SI, Odinokaya MA, Kostina AA. Suetov AA, et al. Among authors: kostina aa. Bull Exp Biol Med. 2021 May;171(2):286-291. doi: 10.1007/s10517-021-05213-4. Epub 2021 Jun 26. Bull Exp Biol Med. 2021. PMID: 34173098
29 results