Spellman RA - Search Results

1

Comparative analysis of micronucleus induction and DNA damage biomarkers in TK6 and A375 cells using flow cytometry.

Sun X, Spellman RA, Engel M, Rubitski E, Schuler M. Sun X, et al. Among authors: spellman ra. Environ Mol Mutagen. 2024 Jan-Feb;65(1-2):25-46. doi: 10.1002/em.22585. Epub 2024 Feb 9. Environ Mol Mutagen. 2024. PMID: 38333939

2

The rat gut micronucleus assay: a good choice for alternative in vivo genetic toxicology testing strategies.

Coffing S, Engel M, Dickinson D, Thiffeault C, Spellman R, Shutsky T, Schuler M. Coffing S, et al. Environ Mol Mutagen. 2011 May;52(4):269-79. doi: 10.1002/em.20616. Epub 2010 Sep 24. Environ Mol Mutagen. 2011. PMID: 20872852

3

Phenolphthalein induces centrosome amplification and tubulin depolymerization in vitro.

Heard PL, Rubitski EE, Spellman RA, Schuler MJ. Heard PL, et al. Among authors: spellman ra. Environ Mol Mutagen. 2013 Jun;54(5):308-16. doi: 10.1002/em.21781. Epub 2013 May 16. Environ Mol Mutagen. 2013. PMID: 23677914

4

Impact of cell cycle delay on micronucleus frequency in TK6 cells.

Sobol Z, Spellman RA, Thiffeault C, Dobo KL, Schuler M. Sobol Z, et al. Among authors: spellman ra. Environ Mol Mutagen. 2014 Jan;55(1):64-9. doi: 10.1002/em.21810. Epub 2013 Aug 28. Environ Mol Mutagen. 2014. PMID: 23982927

5

Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.

Bryce SM, Bernacki DT, Bemis JC, Spellman RA, Engel ME, Schuler M, Lorge E, Heikkinen PT, Hemmann U, Thybaud V, Wilde S, Queisser N, Sutter A, Zeller A, Guérard M, Kirkland D, Dertinger SD. Bryce SM, et al. Among authors: spellman ra. Environ Mol Mutagen. 2017 Apr;58(3):146-161. doi: 10.1002/em.22083. Environ Mol Mutagen. 2017. PMID: 28370322 Free PMC article.

6

A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells.

Sun X, Rubitski E, Spellman RA, Engel M, Schuler M. Sun X, et al. Among authors: spellman ra. Environ Mol Mutagen. 2022 Jun;63(5):230-245. doi: 10.1002/em.22496. Epub 2022 Jun 30. Environ Mol Mutagen. 2022. PMID: 35703118

7

Improving dose selection and identification of aneugens in the in vitro chromosome aberration test by integration of flow cytometry-based methods.

Muehlbauer PA, Spellman RA, Gunther WC, Sanok KE, Wiersch CJ, O'Lone SD, Dobo KL, Schuler MJ. Muehlbauer PA, et al. Among authors: spellman ra. Environ Mol Mutagen. 2008 May;49(4):318-27. doi: 10.1002/em.20387. Environ Mol Mutagen. 2008. PMID: 18366097

8

Development and validation of an in vitro micronucleus assay platform in TK6 cells.

Sobol Z, Homiski ML, Dickinson DA, Spellman RA, Li D, Scott A, Cheung JR, Coffing SL, Munzner JB, Sanok KE, Gunther WC, Dobo KL, Schuler M. Sobol Z, et al. Among authors: spellman ra. Mutat Res. 2012 Jul 4;746(1):29-34. doi: 10.1016/j.mrgentox.2012.02.005. Epub 2012 Mar 13. Mutat Res. 2012. PMID: 22445949

9

Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay.

Cheung JR, Dickinson DA, Moss J, Schuler MJ, Spellman RA, Heard PL. Cheung JR, et al. Among authors: spellman ra. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jan 1;777:7-16. doi: 10.1016/j.mrgentox.2014.11.002. Epub 2014 Nov 15. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25726170

10

Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents.

Bryce SM, Bemis JC, Mereness JA, Spellman RA, Moss J, Dickinson D, Schuler MJ, Dertinger SD. Bryce SM, et al. Among authors: spellman ra. Environ Mol Mutagen. 2014 Aug;55(7):542-55. doi: 10.1002/em.21868. Epub 2014 Apr 23. Environ Mol Mutagen. 2014. PMID: 24756928

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